Analysis Of Clinical And Laboratory Examinations Related To Early Identification Of Lobar Pneumonia Caused By Mycoplasma Pneumoniae And Bronchopneumonia

Objective : Mycoplasma pneumoniae infection is common in pediatric respiratory diseases,which can easily cause lower respiratory tract infection and extrapulmonary complications.By collecting the cases of lobar pneumonia and bronchial pneumonia caused by Mycoplasma pneumoniae infection,the blood routine,inflammatory infection index,immune index and clinical symptoms were analyzed in order to provide basis for early clinical differentiation of lobar pneumonia and bronchial pneumonia caused by Mycoplasma pneumoniae,and to guide clinical medication.Methods:A total of 69 children with Mycoplasma pneumoniae pneumonia were selected from the General Hospital of Northern Theater Command from January 2018 to December 31 2018.Among them,28 cases were diagnosed as bronchopneumonia at admission,28 cases were corrected at discharge,41 cases were diagnosed as bronchopneumonia at admission and discharge.Their clinical symptoms and serological examinations were carried out.The collected data were analyzed by SPSS 24.The software was used for statistical analysis.Results:1.The proportion of neutrophils,eosinophils and platelets in lobar pneumonia group was higher than that in bronchopneumonia group,while the proportion of lymphocytes was lower than that in bronchopneumonia group(P < 0.05).There was no significant difference in white blood cell count and hemoglobin between the two groups(P > 0.05).2.CRP,PCT,SAA and AST in lobar pneumonia group were higher than those in bronchopneumonia group,with statistical significance(P < 0.05).3.IgA in lobar pneumonia group was significantly higher than that in bronchopneumonia group(P < 0.05).There was no significant difference in IgG,IgM and IgE between lobar pneumonia group and bronchopneumonia group(P > 0.05).4.The fever,fever time,gastrointestinal reaction and pleural effusion in lobar pneumonia group were higher than those in bronchopneumonia group,and the difference was statistically significant(P < 0.05).There was no significant difference in the incidence of wheezing between lobar pneumonia group and bronchopneumonia group(P > 0.05).Conclusion:1.In blood routine,the proportion of neutrophils,eosinophils and platelet count in lobar pneumonia group were higher than those in bronchopneumonia group,while the proportion of lymphocyte was lower than that in bronchopneumonia group.It has guiding significance for early clinical identification of lobar pneumonia and bronchial pneumonia caused by Mycoplasma pneumoniae,indicating that the larger the inflammation caused by Mycoplasma pneumoniae,the heavier the infection.2.Inflammatory infection index,CRP,PCT and SAA in lobar pneumonia group were higher than those in bronchopneumonia group,indicating that the larger the lesion,the heavier the infection index.3.AST in lobar pneumonia group is higher than that in bronchopneumonia group,which indicates that the more severe the inflammation is,the more likely the liver damage will occur.Therefore,early detection of increased liver enzymes in clinic can provide a basis for early identification of lobar pneumonia and bronchopneumonia caused byMycoplasma pneumoniae.4.Immunoglobulin IgA in lobar pneumonia group was higher than that in bronchopneumonia group,suggesting that the more serious the disease was,the more serious the immune damage was.IgG,IgM and IgE had no significant difference compared with bronchopneumonia group,but IgE in both groups was significantly higher than the normal range.Considering that Mycoplasma pneumoniae infection can cause airway hyperresponsiveness,but the incidence was not related to the severity of the disease.5.The incidence of fever,fever time,gastrointestinal reaction,pleural effusion and other clinical symptoms in lobar pneumonia group is higher than that in bronchopneumonia group,while the incidence of asthma is not different from that in bronchopneumonia group.This indicates that the persistent fever,gastrointestinal reaction and pleural effusion in the early stage of Mycoplasma pneumoniae infection can provide reference for the development of lobar pneumonia.6.Most previous studies on Mycoplasma pneumoniae pneumonia show that the age of children with lobar pneumonia is higher than that of bronchopneumonia group.There is no statistical significance between the two groups.In order to differentiate the Mycoplasma pneumoniae pneumonia of children from lobar pneumonia according to age group in the future,it is necessary to think about the development of lobar pneumonia.