Relationship Between Serum Total Bilirubin And Prognosis In Patients With Acute Coronary Syndrome After Percutaneous Coronary Intervention

Objective: Through the investigation of the incidence of major adverse cardiovascular events(MACE)after percutaneous coronary intervention(PCI)in acute coronary syndrome(ACS)patients,the relationship between serum total bilirubin(STB)level and prognosis in ACS patients was explored.Methods: 2850 ACS patients who underwent PCI at our hospital between Jun 2009 and Jan 2017 were consecutively included in the study through information retrieval from the medical records system.The patients were followed up by telephone to determine the incidence of MACE within one year of PCI,and a total of 2770 patients who completed follow-up were divided into Groups A,B and C.By performing survival analysis using the Cox proportional hazards model,the incidence of MACE in patients of the three groups were analyzed.Results: Results of follow-up revealed no significant differences in the incidence of MACE and cardiac death among the three groups within 30 days after PCI.Within one year postoperatively,significant differences existed in MACE incidence rate(HR0.522,95%CI: 0.372-0.733,p<0.001)and cardiac death rate(HR0.452,95%CI: 0.293-0.704,p<0.001)between groups B and A while also in MACE incidence rate(HR0.443,95%CI: 0.312-0.631,p<0.001)and cardiac death rate(HR0.363,95%CI: 0.232-0.583,p<0.001)between groups C and A.Conclusion: Both long-term MACE incidence rate and cardiac death rate after PCI were higher in patients with low STB levels.