| Background and Objective:Persistent postural-perceptual dizziness(PPPD)is a chronic functional disease defined in recent years.As the main diagnosis and comorbid diagnosis,it affects nearly half of patients with chronic dizziness,at the same time,nearly 1/4 of acute or paroxysmal patients with vestibular disease may have PPPD-like symptoms within 1 year.Vestibular rehabilitation therapy can be used as an effective intervention to treat PPPD.The SRM-? can stimulate the full flow of endolymph in semicircular canal directions,thereby providing positional stimulation information in a specific direction to the central center of the vestibular nuclear complex,which can be used as a passive vestibular rehabilitation method.The purpose of this study is to perform vestibular rehabilitation of PPPD patients through the SRM-?,to evaluate their therapeutic effects on PPPD.Methods:(1)Research objects: 40 patients with PPPD who were treated in the outpatient department of the Department of Neurology of the First Hospital of Jilin University from March 2019 to February 2020.Inclusion criteria are 18-65-year-old patients who meet the diagnostic criteria for PPPD in ICD-11 issued by the WHO International Classification of Diseases in 2018.Active neurootology and other neurological diseases,neuroimaging examination and vestibular function examination showed obvious abnormalities were excluded,as well as persistent dizziness caused by drugs.(2)Research method: According to different treatment methods,patients were divided into observation group and control group.The observation group was treated with drug therapy combined with SRM-? system adjuvant therapy,while the control group was treated with conventional drugs.Before and after the 1 month of treatment,the patients were evaluated by scales.The evaluation results were statistically analyzed using SPSS 23.0: 1)The severity of dizziness and balance disorders and their impact on life were evaluated through the DHI scale;2)Evaluate the degree of anxiety and depression of patients by HAMA scale and HADM scale;3)Use Berg balance scale to evaluate the patient's ability to actively shift the center of gravity and posture control ability;4)Evaluate the subjective treatment effect of patients through the subjective curative effect evaluation scale.compare the difference between the two groups.Result:(1)The study included 40 patients,20 in each group.There was no statistical difference between the two groups of patients in general data(p> 0.05),indicating that the baseline data of the two groups of patients were balanced and comparable.(2)Before the treatment,patients in the rehabilitation group and the control group were evaluated by the DHI scale.There was no statistical difference between two groups of patients in the scores of total and each item of the DHI scales before treatment(p> 0.05);After 4 weeks of treatment,the DHI scale scores of two groups' patients got before and after treatment were compared.The results showed that the DHI scale scores of the two groups' patients after treatment were lower than before treatment,the difference was significant(p <0.05);The table score is lower than the control group,and the difference is significant(P <0.05).(3)Before the treatment,patients in two groups were evaluated by the HAMA scale.There was no statistical difference in the scores of the HAMA scale between the two groups(p> 0.05);after 4 weeks of treatment,the patients in the control group and the rehabilitation group were measured before and after treatment HAMA scale scores were compared,and the results showed that the HAMA scale scores of the two groups of patients after treatment were lower than before treatment,and the difference was significant(p <0.05);the HAMA scale scores of patients in the rehabilitation group after treatment were lower than the control group,the difference Significant(P <0.05).(4)Before treatment,the patients in the control group and the rehabilitation group were evaluated by the HAMD scale.There was no statistical difference in the scores of the HAMD scale between the two groups of patients(p> 0.05);after 4 weeks of treatment,the patients in the control group and the rehabilitation group were measured before and after treatment.The results showed that the HAMD scale scores of the two groups after treatment were lower than before treatment,and the difference was significant(p <0.05);but there was no statistical difference between the two groups of patients after treatment(p> 0.05).(5)Before the treatment,patients in the control group and the rehabilitation group were evaluated by the Berg balance scale.There was no statistical difference in the scores of the Berg scale between the two groups(p> 0.05);after 4 weeks of treatment,the patients in the control group and the rehabilitation group were measured,the results showed that the Berg scale scores of the two groups of patients after treatment were not statistically different than before treatment(p> 0.05).Conclusion:(1)The SRM-? system combined with anxiolytic drug adjuvant therapy and simple anti-anxiety drug therapy are both effective in improving the physical symptoms,mood and dysfunction caused by dizziness in PPPD patients.The SRM-? system combined with anti-anxiety drug adjuvant therapy is better than the simple application of anti-anxiety drugs in improving patients 'dizziness symptoms.(2)SRM-? system combined with anxiolytic drug adjuvant therapy and simple anti-anxiety drug therapy can improve patients' anxiety symptoms.SRM-? system combined with anti-anxiety drug adjuvant therapy is better than pure anti-anxiety drug in improving anxiety.(3)SRM-? system combined with anxiolytic drug adjuvant therapy and simple anti-anxiety drug therapy can improve patients' depressive symptoms.There is no significant difference between the SRM-? system and the anxiolytic drug adjuvant therapy in improving patients' depression compared with the use of anxiolytic drugs alone.(4)PPPD patients have no obvious obstacles to movements such as sitting and standing,static balance,active center of gravity transfer,and the risk of falling is low.SRM-? system combined with anti-anxiety drug adjuvant therapy and simple anti-anxiety drug therapy have no significant improvement in this regard. |
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