Value Of Thromboelastography In Evaluating Early Neurological Deterioration In Patients With Acute Cerebral Infarction

Objective:To explore the value of thromboelastography in the evaluation of early neurological deterioration(END)and short-term prognosis in patients with acute cerebral infarction.Methods:Ninety-six patients with acute cerebral infarction from Jan,2018 to Dec,2018 were selected from Department of Neurology of Xiangyaping Coal Mine Cooperative Hospital.All patients were examined by TEG after admission and divided into END group and non-END group based on whether END appeared after 3 days.The differences in baseline data,cerebral infarction site,TEG parameters and CCTs index were analysed between the two groups,multivariate logistic regression model was used to analyze the risk factors of END and short-term prognosis.Results:The comparison of baseline data between the two groups showed that the NIHSS score,CRP and apolipoprotein B levels in the END group were higher than those in the non-end group(P<0.01).There was no significant difference in different infarction sites between the two groups(P>0.05).The comparison of TEG parameters and CCTs index between the two groups showed that RT,KT and APTT in the END group were lower than those in the non-end group(P<0.05).Multivariate Logistic regression analysis showed that the NIHSS score,CRP,apolipoprotein B,APTT and the shortening of RT were independent risk factors for the occurrence of END after acute cerebral infarction.Conclusion:The measurement of thromboelastographic parameters,the NIHSS score,CRP,apolipoprotein B,and APTT can be used as the index to predict the END and short-term prognosis in patients with acute cerebral infarction.