A Study On The Relationship Between Memory And Related Brain Region Changes In People Exposed To Auto Accident Trauma

Object To explore the relationship between changes in memory content and related brain regions in patients with PTSD caused by car accident trauma.Method 1.Research object: A total of 117 subjects were selected from December 2018 to November 2019 who experienced a traumatic accident in a car accident on a 300-kilometer highway in Shihezi City and underwent voluntary MRI and follow-up.2.Research tools: General Information Questionnaire,Chinese Version of Wechsler Memory Scale(CWS-RC),Post Traumatic Stress Disorder Assessment Scale(PCL-5),Adult Version of Eysenck Personality Questionnaire(EPQ),and Functional magnetic resonance imaging(fMRI).3.Implementation process(1)Collect the general information of the trauma-exposed person on the day of the car accident trauma;investigate the car accident trauma event,collect the driving recorder and road monitoring video on the scene of the car accident,and organize it into a written record,according to the location of the car accident trauma event Reasons,characters,events and processes are organized into volumes;(2)On the second day after the trauma of the car accident,the subjects were assessed the memory content and CWS-RC related to the traumatic event,and the fMRI examination was completed within 1 week;(3)The memory contents of the subjects were evaluated on days 7,15,30,60,and 90 after the car accident trauma,and the PCL-5 scale examination was performed after 30 days,and the second fMRI examination was performed on day 60.On the 90 th day,the CWS-RC scale evaluation was completed again.According to the DSM-5 diagnostic criteria and confirmation by two psychiatrists with more than one attendance,17 were in the PTSD group and 100 were in the non-PTSD group.Result: 1.The first CWS-RC scale examination found that the PTSD group had higher visual regeneration and score scores than the non-PTSD group,and the difference was statistically significant(P <0.05).During the second CWS-RC test,the PTSD group was higher than the non-PTSD group in picture memory,visual recognition,visual regeneration,associative memory,comprehension memory,and back score scores(P <0.05).(Carefully,whether it is the first time or the second time,why not compare two times)2.The second fMRI examination found that compared with the non-PTSD group,the volume of the right prefrontal lobe of the PTSD group was reduced(GRF correction),and the difference was statistically significant(P <0.01).3.Compared with the first fMRI examination,the second fMRI examination found that the volume of the left central groove cover and cingulate gyrus of the PTSD group was reduced(GRF correction),and the difference was statistically significant(P <0.01).4.The memory impairment caused by the exposure of the car accident traumatic event is positively correlated with the volume changes of the right frontal lobe and anterior cingulate gyrus in patients with PTSD.Conclusion: 1.The memory function of PTSD patients continues to be impaired.2.Compared with the non-PTSD group,the volume of the right frontal lobe,anterior cingulate gyrus,and central groove cover in the PTSD group was reduced.3.The memory damage caused by the exposure of car accident traumatic events is related to the changes in the volume of the right frontal lobe and anterior cingulate gyrus in patients with PTSD.