Clinical Value Of Upper Airway MSCT Measurement In Adult Male Patients With Moderate To Severe OSAHS

Objective128-slice spiral CT was used to measure OSAHS adult male patients in two different breathing phases: awake state and Müller state.OSAHS was evaluated based on changes in upper airway morphology,pharyngeal compliance,and changes in pharyngeal wall thickness.The obstruction of the upper airway of adult male patients at different levels and in different regions provides a strong basis for accurate diagnosis and treatment.At the same time,it explores the pathogenesis factors and pathogenesis related to OSAHS,and fully prepares for clinical diagnosis and treatment of adult male patients with OSAHS.MethodsA total of 52 adult male patients with OSAHS who were treated in the Department of Otorhinolaryngology of the First Affiliated Hospital of Nanchang University from February 2019 to January 2020 were selected,of which 24 were moderate patients and 28 were severe patients.128-slice spiral CT was used to awake patients.Scanning on two different breathing phases: state and Müller state,to measure the volume,airway length,total thickness of the pharyngeal wall in each area of the airway,and the diameter of the smallest plane in each area of the airway.The length and area were calculated,and the corresponding compliance of the pharyngeal cavity was calculated.The length and thickness of the soft palate were measured.Müller motion scans were performed on 20 Immaculate adult male patients who underwent cervical CT scans,and the measurement results were recorded.Finally,each measurement result is analyzed statistically.Results1.There was no statistical difference in age between the OSAHS group and the normal group,P = 0.127> 0.05,the BMI of the OSAHS group was significantly larger than that of the normal group,and the difference was statistically significant(P <0.01).2.The soft palate thickness and soft palate length in the awake state of the OSAHS group were significantly larger than those in the normal group,and the differences were statistically significant(P <0.01).3.The soft palate thickness and soft palate length in the Müller state of the OSAHS group were significantly larger than those in the awake state,and the differences were statistically significant(P <0.01).4.In the OSAHS group,the total thickness of the pharyngeal wall in the posterior soft palate region and the posterior tongue area in the Müller state was significantly greater than in the awake state,and the difference was statistically significant(P <0.01).There was no statistical difference in the total thickness of the pharyngeal wall in the posterior epiglottic area.,P = 0.08> 0.05.5.The total thickness of the pharyngeal wall in the awake state in the OSAHS group was significantly larger in all areas of the airway(except the nasopharyngeal area)than in the normal group,and the difference was statistically significant(P <0.05).6.The awake state of OSAHS group was significantly larger than that of normal group in volume of nasopharynx,posterior epiglottis,total airway volume,and airway length,the difference was statistically significant(P <0.05),and there was no statistical difference in other areas(P> 0.05).7.The Müller state of the OSAHS group was compared with the OSAHS awake state.The Müller state of the OSAHS group was significantly smaller than the OSAHS awake state in the soft palate volume and the posterior tongue volume.The difference was statistically significant,P <0.01.8.The minimum obstruction plane area(except for the epiglottic area)of the upper airways in the Müller state in the OSAHS group was significantly smaller than in the awake state,and the difference was statistically significant(P <0.01).9.In the OSAHS group,the lengths of the diameters of the smallest planes in the Müller airway area(except the posterior epiglottic area)were significantly shorter than in the awake state,and the differences were statistically significant(P <0.01).10.Correlation between airway volume,airway length and AHI index in OSAHS group According to statistical results,it is concluded that there is no correlation between airway volume,airway length and AHI index in OSAHS group,P> 0.05.11.Correlation between airway volume,airway length and LSaO2 in OSAHS group According to the statistical results,the volume of the awake soft palate in the OSAHS group and the volume of the soft palate in the Müller state are positively related to LSaO2,P <0.0512.Correlation between total thickness of pharyngeal wall and BMI in airway areas of OSAHS group According to statistical results,it can be seen that the soft palate region,posterior tongue area in the awake state of the OSAHS group,and the pharyngeal wall thickness of the posterior tongue area in the Müller state of the OSAHS group are related to BMI Positive correlation,P <0.0513.The BMI of OSAHS patients increased with the increase of AHI,and there was a significant positive correlation,P <0.01,but there was no correlation between LSaO2 and AHI,P = 0.31> 0.05.14.The soft palate length and soft palate thickness in the awake state and Müller state of the OSAHS group increased with the increase of AHI,and there was a significant positive correlation(P <0.01).15.The compliance of the pharyngeal cavity in the OSAHS group was significantly greater than that in the normal group,and the difference was statistically significant,P <0.01.16.In the OSAHS group,the compliance of the left and right diameter pharyngeal diaphragm of the soft palate region was greater than that of the anteroposterior pharyngeal diaphragm.The difference was statistically significant,P <0.05.Statistical significance,P <0.05.Conclusions1.There is a positive correlation between BMI and disease severity in adult male patients with OSAHS2.The length and thickness of soft palate in adult male patients with OSAHS can undergo morphological changes during sleep,that is,the soft palate becomes longer and the thickness increases,which is one of the important factors that cause the upper airway to collapse.The soft palate length and thickness in sleep state are positive with AHI.Correlation,so the change of soft palate morphology in adult male patients with OSAHS can assess the severity of OSAHS disease to a certain extent.3.The soft palate area is probably the most vulnerable area for the upper airway to collapse.4.The increase of upper airway length is also an important factor in the pathogenesis of OSAHS.5.Increased compliance of the upper airway pharyngeal cavity is related to head and neck fat deposition.6.Measurement of upper airway MSCT can optimize treatment options for adult male patients with OSAHS.