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Research On The Preparation And Application Of Two-dimensional Porous Nano-carbon And Its Composite Materials Derived From ZIFs

Posted on:2021-03-26Degree:MasterType:Thesis
Country:ChinaCandidate:J S MuFull Text:PDF
GTID:2431330611992209Subject:Analytical Chemistry
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Carbon nanomaterials have been of great significance to the fields of sensing,energy conversion and storage,life analysis,and biomedicine as multifunctional economic materials since the 20th century.Rational choosing and designing carbon nanomaterials is the crux to achieving specific application directions efficiently.The emergence of MOFs in 1990s has provided new enlightenment for design and preparation of new carbon nanomaterials.In this paper,MOFs nanoparticles were used as precursors,and corresponding carbon nanomaterials were conceived and prepared.Based on this fact,analytical detection methods such as electrochemical,UV-vis,and fluorescence analysis methods were used to achieve rapid and sensitive detection of target substances.It provides new envisions and methods for the conceiving and preparation of multifunctional nanomaterials and their bioanalytical applications.This paper built optical/electrochemical sensors,CDs,and nanozymatic cascade bioplatform based on ZIFs-derived carbon nanomaterials and utilized them to analyze and determine related targets and biomolecules.The main research contents are as follows:1.Preparation,analysis and application of a 2D multilayer porous carbon nanosheets derived from ZIFsBy exfoliating the KOH-assisted sonic chemical treatment of the thermally activated ZIF-8 particles,a multifunctional 2D multilayer porous N-CNSs was successfully prepared.?1?Based on affluent mass and electron transport characteristics of CNSs,a electrochemical sensing platform was built via the utilization of CNSs modified glassy carbon electrodes,to achieve discrete electrochemical sensing of carcinogenic HQ and CT,respectively;?2?an artificial enzyme sensing platform was constructed using the simulated peroxidase properties of CNSs,and the rapid colorimetric detection of H2O2 was achieved with the help of the colored TMB-oxidized products;?3?CDs were prepared based on CNSs and realized quantitative fluorescence analysis of Fe3+at an excitation wavelength of 315 nm.The 2D multilayer porous N-CNSs obtained by this strategy had a large specific surface area and pore distribution,rich N-doping content,and unique chemical environment,which improved the mass and electron transfer efficiency in reaction systems,thereby improving the detection sensitivity,and enabled highly sensitive sensing of target substances.2.ZIFs-derived porous carbon-based nanozymatic cascade bioplatforms for colorimetric detection of H2O2 and glucoseBased on the multilayer N-doped carbon derived from ZIF-8 as the matrix,the isoelectric point and guiding effect of BSA was used to promote the combination of nanoparticles and carbon nanosheets,and the protein/bimetallic nanoparticles were self-assembly growing into nanozymatic cascade bioplatforms.In addition to retained excellent peroxidase-like activity,BSA-PtAu@CNS also exhibited excellent GOD-like activity by in-situ reduction of Pt and Au nanoparticles on carbon-based nanomaterials.The cascade biological platform proposed based on this strategy had the characteristics of dual enzyme activities,high stability,high efficiency and high sensitivity for glucose sensing.BSA-PtAu@CNS exhibited outstanding manufacturability,scalability,biocompatibility,and stability,and had broad prospects for further research in biomedical field.
Keywords/Search Tags:CNSs, Electrochemical sensing, CDs, Nanozyme, Cascade bioplatform
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