Preparation Of 3D Hierarchical Structure Nickel-based Composites And Research On Glucose Sensing Properties

Glucose provides basic energy for human life activities and is an important metabolic intermediate of the body.However,high levels of glucose in the body can cause a variety of metabolic disorders?such as diabetes?.Therefore,the development of reliable and sensitive blood glucose detection methods is of great significance for the clinical diagnosis of diabetes control.Over the past few decades,enzyme sensors have received extensive attention for their excellent selectivity.However,because enzymes are susceptible to temperature,humidity,p H,toxic chemicals and other factors,they still have many limitations in further practical applications.Therefore,in order to improve the stability of the sensors,people increasingly favor the development of non-enzymatic glucose sensors.In this paper,a reasonable microstructure with the changeable chemical composition of the electrode materials was designed.3D multistage nickel-based bimetallic composites were prepared by using flexible carbon fiber cloth as the conductive substrate and transition metal compounds as the active material.The specific contents are as follows:?1?The 1D precursor basic cobalt carbonate?CCH?was introduced by hydrothermal method as a support,and then a one-step hydrothermal reaction was performed to prepare 2D nickel-iron layered double hydroxide nanosheets?Ni Fe LDHs?,and finally 3D multistage structure?CC@CCH Ni Fe LDH?was obtained.Analysis of electrochemical data shows that the sensor has excellent catalytic performance for non-enzymatic glucose oxidation,with a sensitivity of up to 6610?A·m M^-1·cm^-2,a fast response speed,reaching a steady state value within 6 s,and a wide linear detection range(10?M^-1m M),lower detection limit?3.3?M?and good selectivity for high concentrations of interferences.?2?A novel 3D multistage structural composite was designed.First,a simple one-step hydrothermal method was used to synthesize basic cobalt carbonate nanorod arrays?CC@CCH?on carbon cloth.The well-arranged basic cobalt carbonate nanorods were used as guide templates and the support of metal organic framework?MOFs?.Finally,nickel-cobalt layered double hydroxide nanosheet arrays?Ni Co LDHs?were prepared using MOFs as the cobalt source and the sacrificial template.Therefore,a composite material with self-supporting hybrid array structure?CC@CCH MOF LDH?without binder and conductive agent was constructed.Test results show that the sensor possesses higher sensitivity(4310?A·m M^-1·cm^-2),lower detection limit?110 n M?,wider linear detection range?1?M-2 m M?,and the response time does not exceed 6 s.In addition,the sensor has good selectivity.