Research On The Angular Acceleration Sensing Characteristics Of Artificial Semicircular Canals

From the evolution of lower animals to higher animals,humans have evolved a pair of complex,delicate,and sensitive balanced sensory organ-semi regulatory tubes.They sense the angular acceleration using the ampullary sacral-endocrine lymph-coupling inertial system and perform spatial orientation.Keep clear vision and body balance.Due to physiological reasons,it is difficult to directly observe and measure the mechanical response of the semicircular canal,and there is a lack of in-depth understanding of its perception mechanism.In this study,artificial materials were used to replace the inertial tissue inside the semicircular canals.Artificial sensor hair cells containing metal core piezoelectric fibers were used instead of sensory ciliated cells.A coupled biomimetic artificial semicircular canal system with similar biomechanical properties was designed and prepared.Based on this system,the mechanism of angular acceleration perception of the human semicircular canal is studied from the local to the overall sequence,including the functional mechanism of the apex-endocrine system,the angular acceleration sensing mechanism of a single semi-regular tube,and the angular acceleration sensing mechanism of three semi-regular tubes.Establish a model that reflects semi-regulatory work processes,working principles,and signal processing mechanisms,and conduct experimental verification.This topic will help us to understand in depth the functional principles of the semi-regulatory system and promote the development of functional check techniques in the vestibular system.The project selects suitable artificial material devices to replace the corresponding human biological tissues in the physiological semicircular canal,and designs and prepares artificial semicircular canals.It simulates the structure and function of human physiological semi-regulatory tubes at both macroscopic and microscopic levels and is a coupled bionic system.At the macro level,the artificial semi-regulatory tubes and human physiological semi-regulatory tubes have a high degree of similarity in terms of the overall structure and the working principle of the inertial system;the microscopic level refers to the sensor elements SMPF in the artificial semi-regulatory tubes and the sensory hair cells in the human physiological semi-regulatory tubes.There is a high degree of similarity in structure and function.The main content of this article is as follows:(1)To study the functional mechanism of the apical-endolymphatic system in ampulla.Imitating the structure of the ampulla in the semi-regulatory tube of human physiology,SMPF was used as a sensing element,and a structure-like circular film-like artificial ampulla was prepared.Artificial ampulla will produce concave and convex deformation under the effect of liquid loading.Design and preparation of straight artificial semicircular canal which can directly observe and measure artificial ampulla concave and convex deformation.When the head is rotated,the inner lymph and the ampulla gelatine top are constrained by the inertial law and the movement reaction occurs.The glue tip shifts the curved cilia of the sensory hair cells connected with it,and after complex biochemical reactions,the nerve signals are generated.Based on this structure,the relationship between the internal liquid loading,the deformation of the rubber dome,and the cilia bending was studied when the semi-regular tube was stimulated by a straight line.The corresponding biomechanical model was established to study the angular acceleration sensing mechanism of a single human physiological semi-regular tube.(2)Design and preparation of biomimetic one-dimensional artificial semicircular canals to study the mechanism of angular acceleration perception of single human physiological semicircular canals.The shell of the shape of the human physiological semi-regular tube structure was designed and prepared,and the prepared artificial ampulla was fixed on the inner wall of the ampulla part of the shell of the PL A material,and a one-dimensional artificial semicircular canal was designed and prepared.Based on the research content(1),based on a one-dimensional artificial semicircular canal,the relationship between the angular acceleration(angular displacement)of the semicircular canal and the deformation of the ampulla gelatinum crest and cilia bending during the occurrence of plane rotation was studied.Biomechanical model.(3)To simulate the three-dimensional structure of human physiological semi-regulatory tubes,and to design and prepare three-dimensional artificial semicircular canals.When the head of the human body rotates,the three groups of sensory signals generated by the three ampullaxes should be related to each other,and the spatial angular acceleration(angle)is initially obtained because three semicircular canals communicate with each other and the internal lymph fluid can flow.The specific direction and size of the displacement).The design and preparation of the artificial semi-regular tube angular acceleration sensor overcomes the disadvantages of traditional sensors such as high resonance frequency,mismatch with the human body,low precision,complicated processing,and large driving force of conventional sensors,and excessive power loss.The coupled bionic artificial semi-regulatory tube system prepared by the subject has a similar structure and working principle as the human physiological semi-regulatory tube.The establishment of human semi-regulatory solid model and the study of its sensing characteristics will help us to better understand the structure and relationship of semi-regulatory tubes,work processes and working mechanisms,and verify and discover the pathology and etiology of related diseases.The built model can be easily verified and corrected through experiments,with high authenticity and reliability.