The Value Of MSCTE In Imaging Diagnosis Of Small Bowel Inflammatory Lesions

Objective:To provide a basis for selecting appropriate oral contrast agent of MSCTE by contrastively analyzing the small intestine expansion degree of three oral contrast agents.Methods: Totally 60 cases of patients who needed small intestine MSCTE scan in our hospital were randomly selected and were randomly divided into three groups: 2.5% isosmotic mannitol as group A,3% iohexol as group B,purified water as group C,with 20 cases in each group,and approximately 2000 mL of corresponding solution was taken orally within about 1-4h prior to examination.All the patients underwent CT plain scan arterial phase and venous phase enhanced scan,delay scan was added if necessary,the resulting data were imported into workstation to conduct image 3D reconstruction,the reconstructed image was analyzed by two associate chief physicians or above level using blinding method to judge the expansion degree of small intestine,finally,the obtained data were statistically analyzed.Results: The differences in small intestine expansion degree among three different oral contrast agents were statistically significant,wherein,the filling effect in group A(2.5% isosmotic mannitol group)was the best,which had statistical difference compared with that of group B(3% iohexol group)or group C(purified water group)(p<0.05),while the difference between group B(3% iohexol group)and group C(purified water group)was not statistically significant(p>0.05).The comparison within groups revealed that the expansion filling effect in ileum was the best,which was distinctly better than that of jejunum or duodenum,that of jejunum was second only to ileum,and duodenum was the worst one.Conclusion: 2.5% isosmotic mannitol solution has the best small intestinal canal expansion effect among the whole group,the intra-intestinal mucosa and enterocutaneous lesions are displayed on the image clearly,the small intestinal lesions can be found clearly,which is the first choice of oral intestinal contrast agent for MSCTE.Objective:To explore the imaging diagnostic value of MSCTE in inflammatory lesions of small intestine,and improve the diagnostic rate of small intestine inflammatory lesions.Methods:Totally 103 cases patients with clinically suspected small intestine inflammatory lesions who met inclusion criteria of this study orally took 2000 m L of 2.5% isosmotic mannitol solution as requested before scanning,all the patients underwent CT plain scan arterial phase and venous phase enhanced scan,delay scan was added if necessary,the site,range,shape,enhancement pattern and relationship with adjacent tissues of small intestine inflammatory lesions were observed,and the contrastive analysis was carried out between the MSCTE diagnosis result and the final clinical diagnosis result.Results: In the 103 cases of suspected patients,58 cases were diagnosed as small intestine inflammatory lesion,which was consistent with the final clinical comprehensive diagnosis result.In those 58 cases of patients,Crohn's disease was occurred in 20 cases,enterophthisis was occurred in 8 cases,connective tissue enteritis was occurred in 5 cases(lupus enteritis in 4 cases,sicca syndrome colitis in 1 case),bacterial enteritis was occurred in 5 cases,eosinophilic gastroenteritis was occurred in 2 cases,ulcerative colitis involved small intestine was occurred in 7 cases,enteritis anaphylactica was occurred in 1 case,and nonspecific enteritis was occurred in 10 cases.Conclusion:MSCTE can improve the diagnostic rate of small intestine inflammatory lesions to some extent,which has a certain popularization value due to it has both advantages of small intestine follow through and conventional abdominal enhanced CT scan.