Font Size: a A A

Analysis Of Related Factors Of Lung Parenchymal Injury After Pulmonary Embolism

Posted on:2019-09-20Degree:MasterType:Thesis
Country:ChinaCandidate:J SunFull Text:PDF
GTID:2434330566990318Subject:Internal Medicine
Abstract/Summary:PDF Full Text Request
Objective: this article through the analysis of pulmonary thromboembolism(PTE),the clinical data of patients,PTE diagnosis time,explore the delayed diagnosis of PTE and after PTE risk factors of pulmonary infarction(PI),and PI typical imaging findings,in order to identify patients at high risk of developing after PTE PI may occur,which will provide a scientific basis for early diagnosis and treatment.Methods: Analyzed retrospectively from January 2015 to June 2017 in Beijing chaoyang hospital affiliated hospital of Qingdao university and CT pulmonary angiography(CTPA)or pulmonary artery perfusion scan(V/Q)diagnosed patients with PTE,according to the imaging results into the PI and PI group,collects all the PTE patients clinical data,analysis of PI and the PI group respectively in the two groups patients general basic characteristics,the merger risk factors and basic diseases,clinical symptoms and signs and basic life after admission,laboratory and imaging examination results,such as data,final diagnosis information such as time,using t test and chi-square test,Analysis of the correlation between above factors and PI before and after the PTE,summarize the PTE patients with delayed diagnosis rate,analyze the clinical characteristics of patients with delayed diagnosis,seeking for the delay in diagnosis may lead to PTE patients,and summarizes the typical PI radiographic and clinical characteristics,Logistic regression analysis,screening PTE occurred after the independent risk factors of PI.Results: 483 patients with PTE there're a total of 108 cases(22.36%)patients experienced PI,compared two groups of patients with clinical data,patients with general basic characteristics: age,body mass index(BMI),the difference statistically significant(P <0.05),gender differences are not significant(P > 0.05),including the PTE peak of the PI before and after the age of 50 or so;In terms of risk factors,the recent operation(4weeks),smoking and PTE post PI(P BBB 0.05);Combined basic diseases: the first three complications of non-pi group were coronary heart disease,malignancy,lung or deep vein thrombosis.And PI group was ranked the first three complications were: pulmonary or deep vein thrombosis(DVT)history,diabetes,cerebrovascular disease,including coronary heart disease(CHD)is were the risk factors of the PI(P < 0.05),while history of atrial fibrillation,bronchiectasis,diabetes mellitus(DM),COPD,merging,malignant tumor,a history of PTE or DVT has no statistically significant difference(P > 0.05);Clinical symptoms and signs: the difference between pleurisy chest pain and hemoptysis was statistically significant(P<0.05),and there was no significant difference between the two groups of respiratory distress and syncope(P BBB 0.05).Oximetry vital signs: after admission(greater than 110 times/min),blood pressure(less than 100/40 MMHG),body temperature,breathing(> 30 times/min)there were no statistically significant difference(P > 0.05),and laboratory data: oxygen saturation(90%),D-dimer II,myocardial injury markers results,BNP difference is not significant(P > 0.05),imaging examination aspect:Plaque index(embolus block position),the proportion of the central artery involvement,pleural effusion,lower limb vein thrombosis,heart,ultrasound is prompt right cardiac insufficiency difference statistically significant(P < 0.05),while lead electrocardiogram results in chest of T wave inversion and a VR lead s T segment elevation in the PI in the proportion of patients significantly higher(P < 0.05).Line will be statistically significant factors influencing the further Logic linear regression analysis: age,merge coronary heart disease,pleurisy,chest pain,heart,ultrasonic tip right cardiac insufficiency,plaque index,the central artery involvement,low-risk(PTE risk score),electrocardiogram(ecg)lead a VR in st-elevation factors such as statistically significant(P < 0.05),while haemoptysis,pleural effusion,BNP(hf)and lower limb venous thrombosis has no statistical significance(P > 0.05).Analysis of delay in the diagnosis of PTE,found that patients with lung parenchyma injury is a risk factor for patients with PTE delayed diagnosis,the analysis of imaging findings in 483 patients with PTE,substantial damage to the lung instead of 110 patients with pulmonary infarction,PI focal 40 persons in the right lung lobe(37.04%),and those of the upper lobe: 8(7.41%),the middle of the right lung: 5(4.63%),left upper lobe: 9(8.33%),left lower lobe: 22(20.37%),Conclusion: 1.The PI the independent risk factors of PTE were age,merge coronary heart disease,pleurisy,chest pain,heart,ultrasonic tip right cardiac insufficiency,plaque index,the central artery involvement ratio,PTE risk score for low-risk,ecg lead AVR in ST segment elevation.Lung parenchymal injury is a risk factor for delayed diagnosis of PTE.3.Pulmonary infarction with the pulmonary infarction mortality rate was no significant difference,while the old patients with PTE,merging,malignant tumor patients with PTE,embolus block the central artery in patients with PTE,and misdiagnosis(miss)PTE patients mortality is higher.
Keywords/Search Tags:pulmonary embolism, pulmonary parenchymal injury, pulmonary infarction, risk factor, prognosis
PDF Full Text Request
Related items