Investigation On The Incidence And Risk Factors Of Left Ventricular Mural Thrombosis After Acute Myocardial Infarction

Objectives:There are limited data about the incidence,risk factors,prognosis and treatment in Asians with left ventricular thrombus(LVT)after anterior or extensive anterior ST-segment elevation myocardial infarction.Methods:We retrospectively analyzed the data of 1245 patients with anterior or extensive anterior STEMI from January 1,2014 to December 31,2017.LVT was diagnosed by transthoracic echocardiographis at emergency department,on the day of PCI,3 days after PCI and 1 week after PCI.Incidence and risk factors of LVT and systemic embolism(SE)were analyzed.Results:LVT was diagnosed in 39 of 1245 patients(3.9%),26(67%)with extensive anterior STEMI and 13(33%)with anterior STEMI.SE occurred in 1 of 39 patients(2.5%)with LVT,and no SE was found in 40 patients(0%)without LVT;Reduced LVEF(<40%)was more frequently observed in LVT patients and predict LVT(OR=11.696,95%CI:2.620-52.215,P=0.001).Conclusions:In patients after anterior or extensive anterior STEMI,LVT was detected in 3.1%by echocardiography and SE occurred in 2.5%of patients with LVT during within 12 months follow-up.Reduced LVEF(<40%)is an independent risk factor for LVT.