An FMRI Study Of The Effect Of Acupuncture At Yanglingquan On The Sensorimotor Network Of Patients With Hemiplegia In Stroke On Different Sides

Background:Stroke is one of the most important propositions in the current health field in China,with an annual incidence of 246.8 per 100,000 people and a mortality rate of more than 114.8 per 100,000 people per year.The pathological mechanism of stroke lies in ischemic necrosis in different parts of the brain,so there are differences in infarct sites.Numerous studies have proved that there is a lateral difference in brain function,and this laterality is reflected in various aspects of brain function,but there are relatively few studies on this lateral difference in motor function.As a commonly used treatment for stroke,acupuncture is used to treat acupuncture points.On the one hand,most of the acupuncture points are symmetrically distributed and have the potential for laterality.On the one hand,there are also treatments with obvious laterality such as "giant spines" and "counter-thorns" in the theory of acupuncture treatment.Objective:To group the patients with stroke on the left and right sides,and observe the changes in brain functional magnetic resonance before and after needle acupuncture in two groups of patients.Through statistical observation and exploration of the observation results,combined with previous research results,The cerebral function of patients with stroke and its laterality after acupuncture at the Yanglingquan acupoint on the affected side were explored.The possible mechanisms of laterality were interpreted to provide supporting evidence for lateral acupuncture.Methods:A total of 11 patients with right infarction and 8 patients with left infarction were included in the study.Baseline data collection and motor function evaluation were performed by the same investigator.Subsequently,the magnetic resonance room was subjected to a resting state scan of 8 minutes and 10s in order.Acupuncture in Yanglingquan.After acupuncture is completed,acupuncture scanning is started.There is no operation for the first 10s,and the needle is twisted at a frequency of 1Hz for the next 1min.After that,the needle is left for 7min.scanning.The baseline data of the two groups were compared statistically.The magnetic resonance data were processed and counted.The patients in the same group were compared in the resting state and the different regions of interest during needle retention.The intra-group voxel FC was compared within the group.Interstate comparisons were made between resting states,regions of interest during needle retention,and FC of whole brain voxels.Results:There was no significant difference between the two groups of patients in terms of age,duration of disease,and motor function scores.Using the ICA method,the SMN brain network of all patients was extracted,which mainly included most of the parietal lobe,anterior cerebellum,posterior cerebellar lobe,and part of the frontal lobe and temporal lobe.In the resting state,the FC between the left M1 and the right cerebellum is significantly different in patients with cerebral infarction on different affected sides.The right cerebellum is located in the SMN brain network;the right M1 and whole brain voxel FC groups There were differences between the left middle occipital gyrus and the anterior wedge;the resting state of the left cerebral infarction group and the FC of the right M1 and whole brain voxels during the needle retention were different in the left occipital gyrus and the angular gyrus.Conclusion:Based on the results of this study,we can think that the brain function patterns of patients with different affected cerebral infarctions are likely to have certain differences,and this difference may have a certain impact on acupuncture treatment and treatment effect.