Copper-catalyzed enantioselective allylic substitutions with organomagnesium and organoaluminum reagents promoted by N-heterocyclic carbenes for the formation of quaternary stereogenic centers

Chapter one. An overview of Cu-catalyzed enantioselective allylic substitutions with organometallic reagents.;Chapter two. Development of Cu-catalyzed enantioselective allylic alkylations of allylic chlorides with Grignard reagents for the formation of all-carbon quaternary stereogenic centers is disclosed.;Chapter three. Development of Cu-catalyzed enantioselective allylic substitutions of allylic phosphates with alkyl, aryl and heterocyclic aluminum reagents for the formation of quaternary stereogenic centers is discussed.