Antioxidant and anti-proliferative properties of selected grape seed extracts | Posted on:2010-12-02 | Degree:M.S | Type:Thesis | University:University of Maryland, College Park | Candidate:Bloom, Raquel Zorah | Full Text:PDF | GTID:2441390002970522 | Subject:Agriculture | Abstract/Summary: | | This study examined chardonnay, muscadine, concord, and ruby red grape seed oil and flour extracts for antioxidant and anti-proliferative properties. The extracts were tested for total phenolic content, DPPH&bull and ABTS&bull+ radical scavenging capacity and effect against HT-29 cancer cell proliferation.All of the grape seed extracts exhibited ABTS&bull+ and DPPH&bull radical quenching activity. The flour extracts from chardonnay demonstrated the highest ABTS&bull+ radical quenching capacity of 186 mumoles trolox equivalents/g and DPPH&bull radical quenching activity of 30 mumoles trolox equivalents/g. All of the grape seed oil and flour extracts contained significant levels of phenolics. Chardonnay grape seed flour extract displayed the most prominent dose dependent anti-proliferative effect. Muscadine and ruby red, but not concord grape seed flour extracts, also exhibited anti-proliferative activities. The collected data advocate for the potential of grape seed extracts as dietary sources of anti-proliferative and antioxidant components. | Keywords/Search Tags: | Grape seed, Extracts, Anti-proliferative, Antioxidant, Dpph&bull radical quenching activity, Ruby red, Mumoles trolox equivalents/g | | Related items |
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