| Clinical Practice Guidelines (CPGs) are developed to reduce inappropriate variations in clinical practice, to improve health care quality and to control costs. In order to provide patient-specific treatment, the collection and processing of temporal data are vitally important in many clinical settings, especially for chronic diseases. Representation of temporal data within CPGs is a critical issue for computer based guideline development. Our objective is to create an ontology formalism to represent practice-oriented temporal knowledge in a collection of CPGs for chronic diseases. The CPGs selected for the development of the temporal model were on Diabetes. Our methodology is comprised of five steps: identifying the purpose, scope, and users of semantic models; domain analysis and knowledge acquisition; building a conceptual ontological model; building a formal ontological model using Protege; and ontology evaluation. One of the potential applications of our ontological model is its integration with decision support and patient management applications. |