Double esterification-ring-closing metathesis approach for the synthesis of beta-C-trisaccharides

Posted on:2005-11-23

Degree:M.S

Type:Thesis

University:Wayne State University

Candidate:Komanduri, Venukrishnan

Full Text:PDF

GTID:2451390008486272

Subject:Chemistry

Abstract/Summary:

Various diesters needed for the synthesis of differentially linked beta-C-trisaccharides were synthesized by usual functional group transformations. The esters were methylenated using Takai's protocol and cyclized using the second generation of Grubb's catalyst. Hydroboration of the resulting bis-C-glycal produces beta-C-trisaccharide.

Keywords/Search Tags:

Synthesis

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