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A specific RNA-protein interaction in alfalfa mosaic virus: Identification of an RNA binding consensus sequence and conserved RNA determinants

Posted on:1998-02-28Degree:Ph.DType:Thesis
University:Harvard UniversityCandidate:McKinney, Patricia AnselFull Text:PDF
GTID:2463390014479132Subject:Molecular biology
Abstract/Summary:
Alfalfa mosaic virus (AMV) coat protein has multiple functions in the virus life cycle, including the initiation of infection in plants, the regulation of virus replication and virion assembly. AMV coat protein binds specifically to the 3;An AMV amino-terminal RNA binding domain (i.e. coat protein peptides) and a 3;This thesis provides evidence that both RNA and protein determinants are necessary for specific coat protein/peptide binding to AMV...
Keywords/Search Tags:RNA, Protein, AMV, Virus, Binding
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