| Protein posttranslational regulation is a major facet of protein function, and efforts have been made to systematically characterize the level of control of proteins. For example, systematic determination of protein localization, phosphorylation, and interactions have allowed the examination of the regulatory network of the cell. However, the study of the evolution of this underlying regulatory network requires a higher resolution analysis of the sequences that are responsible for this level of control.;The overarching goal of this thesis was to examine the role of the evolution of protein regulatory sequences as a molecular mechanism driving functional diversity. (Abstract shortened by UMI.). |
