Fabrication And Properties Of Antibacterial Materials Based On Superhydrophobic Property And Phototherapy

Bacteria and other microorganisms easily adhere to the surface of various materials,proliferate and even form a mature biofilm,which not only compromises the performances of the materials,but also causes serious infections to human body.Endowing the surface with superhydrophobic property is an extremely effective way to prevent the surface from bacterial contamination.However,the superhydrophobic surface is readily affected by its insufficient stability in the microbial environment,so it lacks a long-term resistance to bacterial adhesion,which in turn leads to persistently bacterial infections.Therefore,the surface endowed with both supehydrophobic and bactericidal properties is highly desired,on which the superhydrophobic surface can repel most of the bacteria while the adhered bacteria can be inactivated,finally resulting in a high-efficient antibacterial surface.In this paper,to overcome the shortcomings of a sole superhydrophobic surface against bacterial contamination,the synergistic antibacterial material integrated with both superhydrophobic property and phototherapy is designed.The synergistic antibacterial material avoids the dependence on traditional antibacterial agents and greatly reduces the development of bacterial resistance,which can improve the antibacterial efficiency,durability and safety of functional materials.The specific research contents are listed as follows:1.The contamination of biological materials surface caused by bacteria seriously threatens human health.It is important to develop biomaterials with excellent antibacterial properties and with less or even no risk of drug resistance.Here,inspired by the superhydrophobic lotus,we use a simple non-solvent induced phase separation method to prepare a superhydrophobic,photodynamic antibacterial composite membrane with micro/nano scale structure.Benefiting from the excellent liquid-repellence,the synergistic antibacterial composite membrane resists most of bacterial adhesion at the initial stage.Subsequently,few of adhered bacteria can be easily eliminated by photodynamic therapy(PDT),in which the bactericidal activity is mediated by cytotoxic reactive oxygen species(ROS)under the visible light illumination,avoiding the risk of antimicrobial resistance.The antibacterial test showed that the antibacterial composite membrane exhibits 100%synergistic antibacterial efficiency against Gram-positive S.aureus,Gram-negative E.coli and P.aeruginosa under visible light irradiation for 20 min.Additionally,whole blood adhesion and self-cleaning tests proved that the composite membrane has good anti-fouling property.The synergistic antibacterial composite membrane may find potential applications as an antibacterial platform for bacterial infection-resistant areas and provide new ideas for the preparation of efficient antibacterial materials.2.Most pathogenic microorganism is mainly transmitted through respiratory droplets.Medical masks can block the route of pathogenic microorganism transmission to protect individuals from disease infection.However,most medical masks cannot be self-sterilized,resulting in an increase in the global economy and resource consumption.Here,we report a solar-induced self-healing superhydrophobic reusable mask(PCNTs-HD₈)with outstanding photothermal performances.The PCNTs-HD₈mask has excellent superhydrophobic properties(WCA:156.8°,RA:5.4°),which prevents bacterial droplets from gathering on the surface of the mask,and exhibits relatively high bacterial anti-adhesive ratios,with50.11%and 60.44%for S.aureus and P.aeruginosa,respectively.The mask shows excellent photothermal antimicrobial performance,which can quickly heat up to80?under simulated solar irradiation(0.2 W cm^-2,300 W Xe lamp).The antibacterial efficiency of S.aureus 89.45%and P.aeruginosa 90.49%can be reached under simulated solar irradiation(10 min).The PCNTs-HD₈still exhibits excellent superhydrophobic and photothermal conversion properties after 12 times of chemical etching,which indicates the feasibility for maintaining high-efficiency synergistic antibacterial efficiency during reusable process.Moreover,the whole blood adhesion and self-cleaning test prove the fact that the mask has the excellent anti-fouling performance.Therefore,PCNTs-HD₈provides good personal protection against the infection of bacteria and other microorganisms.