| As a broad-spectrum antibiotic,chloramphenicol(CAP)is widely used in the aquaculture and aquaculture industries to treat typical animal infectious bacterial diseases such as tuberculosis.After entering the human body through meat products,it can accumulate in the human body and can cause diseases such as aplastic anemia.Therefore,the content of chloramphenicol in meat products needs to be strictly controlled.In terms of accurately detecting chloramphenicol in meat products,electrochemical technology has the advantages of high efficiency,convenience,and low cost,and it is a promising methodfor chloramphenicol detection.As the core of electrochemical sensors,sensitive materials are the key to determining sensor performance.In recent years,carbon nanomaterials have the advantages of good conductivity and controllable structure,making it an ideal sensitive material.At present,carbon-based nanomaterials have been used to construct electrochemical chloramphenicol sensors.Transforming the structural advantages of carbon nanomaterials into excellent performance of sensors is the primary problem that needs to be solved urgently.This paper aims to prepare a high-performance carbon-based electrochemical chloramphenicol sensor.By analyzing the relationship between the structural characteristics of carbon-based nanomaterials and electrochemical sensitivity,a carbon-based sensitive material with excellent performance was obtained,and a high-performance electrochemical chloramphenicol sensor was constructed.First of all,the relationship between the structure of three carbon materials(such as r GO,MWCNTs and CB)and the electrochemical sensitivity performance was analyzed.The influence of the structure of carbon nanomaterials on chloramphenicol sensorswas summarized.Secondly,r GO was selected as a typical carbon nanomaterial to prepared a composite of r GO and Mo S2,an electrochemical chloramphenicol sensor based on it was constructed.The main work content is as follows:(1)A one-step hydrothermal method was used to deposit trace amounts of Mo S2on the surface of carbon-based nanomaterials to prepare three carbon-based hybrids:Mo S2-r GO,Mo S2-MWCNTs and Mo S2-CB.The microstructure characteristics of the three carbon-based composite materials and their sensitivity to chloramphenicol were studied in detail,and the influence mechanism of three different carbon-based nanomaterials on the electrochemical chloramphenicol sensitivity was summarized.r GO has good electrical conductivity and a unique two-dimensional layered structure,which improves the electroactive specific surface area of sensitive materials and the sensitivity of the sensor;MWCNTs show good conductivity and small electric double layer capacitance,the sensor has a lower detection limit and a wider linear range.In contrast,CB does not show obvious advantages in terms of conductivity,and the sensor exhibits relatively poor sensitivity.(2)The r GO with a unique two-dimensional layered structure was selected as a typical carbon nanomaterial,and Mo S2-r GO materials with different r GO content were synthesized.The influence of r GO content on the sensitivity of chloramphenicol was studied,and an electrochemical chloramphenicol sensor with excellent sensitivity was obtained.Compared with Mo S2 and r GO monomer materials,Mo S2-r GO composites show more excellent sensitivity performance to chloramphenicol.The sensitivity and detection limit of the constructed sensor are 4.566?A·?M-1·cm-2 and0.6?M,respectively.The excellent sensitivity performance is mainly attributed to the synergistic effect of Mo S2 and r GO,which improves the conductivity and electroactive surface area of sensitive materials.Through the above two aspects of work,this paper not only provides a new sensing material for the preparation of electrochemical sensors,but also provides experimental results for the influence of carbon nanomaterials on the performance of electrochemical sensors,which has an important reference significance for the application and development of electrochemical sensors. |
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