Redox Isomerization Of Allylic Alcohols And Tandem Reaction Catalyzed By Cp~*Ir Complex

Allyl alcohol is a key raw material for chemical production,many chemical workers have begun to use transition metals to catalyze the isomerization of allyl alcohol to obtain ketone derivatives and generate new chemicals.The traditional classical synthesis method is to prepare carbonyl compounds through the oxidation and reduction of allyl alcohol.However,various equivalents or even excessive amounts of strong oxidants,strong reducing agents and additives are inevitably added during the synthesis process,which causes certain pollution to the environment.Compared with the traditional redox isomerization reaction,the allyl alcohol isomerization is a green,clean,high-efficiency and high-atom utilization method.As modern society pays more and more attention to environmental protection issues,it is particularly important to explore an efficient and green modern organic synthesis method.In this paper,allyl alcohol was studied and a new water soluble catalyst[Cp~*Ir(2,2'-bpy O)(OH)][Na]was synthesized.The transition metal iridium catalyst was used to catalyze the isomerization and transfer hydrogenation of allyl alcohol,which effectively reduced allyl alcohol.The main content is divided into two parts:the first part is to use a water-soluble iridium catalyst[Cp~*Ir(2,2'-bpy O)(OH)][Na]to catalyze the automatic transfer and rearrangement of intramolecular hydrogen of propylene alcohol to ketone in a water solvent to obtain a series of targets with good yield products,the atomic utilization rate reached 100%in this process,and the consumption of chemicals and energy was the least,which was environmentally friendly.In the second part,a series of high-yield saturated alcohols were synthesized by using sodium formation as the hydrogen source,water as the solvent.The transition metal iridium catalyst[Cp~*Ir(2,2'-bpy O)(OH)][Na]was used to isomerize and transfer hydrogenate the allyl alcohol.Synthetic methods demonstrate the potential of transition metals to promote radical tandem catalysis.Moreover,this reaction raw material is cheap and easy to obtain,and the atomic efficiency is high.The"one-pot method"is easy to operate,so this reaction has a high attractiveness,which is in line with the concept of green chemistry in the new era.