Preparation Of Wetting Surface Enhanced Raman Scattering Precision Interface And Research On Its High Sensitivity Effect

With the continuous development of human science and technology,the needs for environmental protection and human health are ever-increasing.Therefore,how to quickly and efficiently detect such as environmental pollutants,chemical reagents and trace harmful elements in food is of great significance.Raman spectroscopy has attracted widespread attention because of its specific molecular fingerprint recognition capabilities and non-destructive properties.However,due to the small scattering cross section of Raman spectroscopy,the defect that the signal is usually pretty weak has caused the detection application of conventional Raman spectroscopy in trace analytes to be greatly restricted.Therefore,it has important application value for the development of highly sensitive surface-enhanced Raman scattering（SERS）substrates with plasma nanostructure applications.In recent years,the regulation of surface wettability has attracted extensive attention.Therefore,this paper combined wettability with SERS substrate to realize efficient and highly sensitive detection.In this paper,super-hydrophobic and super-hydrophilic substrates can be obtained quickly and efficiently by using ultra-fast laser and magnetron sputtering deposition system,without complicated lithography process or modification of highly polluting chemical reagents.The super-hydrophobic substrate,due to the low solid-liquid contact surface,can effectively gather the probe molecules in a small area during the drying process to increase the relative concentration and achieve the effect of improving the sensitivity.The enhancement factor was up to 4.82×10⁸,the relative standard deviation of uniformity is less than 15%,and the minimum concentration of Rhodamine 6G（R6G）solution is 10^-11 M.On this basis,adding high refractive index Ti O₂ dielectric layer can make the substrate become super-hydrophilic.In the detection process,the lower liquid level height can be directly detected without drying process.Moreover,the high refractive index layer can further improve the sensitivity of the substrate to make up for the weakness of signal weakening due to the dispersion of probe molecules under hydrophilic condition,and the enhancement factor can reach 1.63×10⁹.In addition,the substrate is combined with Polydimethylsiloxane（PDMS）microfluidic channel for real-time detection,and the R6G solution inside the channel is successfully detected.This study has great significance for the practical application of SERS.