Study On The Addition Reaction Of Bismuth Piperazine Complex For The Construction Of C-X（O,C）bond

Due to the particularity of their structure,diarylmethane compounds have unique physical and chemical properties,and are widely used in agricultural products,pharmaceuticals,and materials science.As a result,the construction of diarylmethane compounds and their derivatives has also become a sopthot continuously.P-Methylenequinone compounds（p-QMs）are a class of bifunctional groups containing carbonyl groups and cyclohexadiene.Because of their unique structure,they produce neutral and amphoteric resonance strucutres,which provides a good electron acceptor for 1,6-addition reactions and one of the efficient substrates for the construction of diarylmethane compounds.In this thesis,a metal bismuth complex(C₄H₁₂N₂)₂[BiCl₆]Cl·H₂O was designed and prepared in this thesis,and the structure was characterized by X-ray.In this thesis,the metal bismuth complex(C₄H₁₂N₂)₂[BiCl₆]Cl·H₂O is used to catalyze the 1,6 addition reaction of p-methylenequinone compounds and alcohol derivatives.Through a series of single factor analysis experiments,conditions were optimiazed in terms of catalyst,solvent,reaction equivalent ratio,etc.,and the best reactions were screened out.Finally,it is proved that the bismuth catalyst can be recycled in this reaction system.Under the optimal conditions,a series of diarylmethane derivatives were obtained in a short time and characterized by MS,1H NMR,13C NMR and other means.In addition,the metal bismuth complex((C₄H₁₂N₂)₂[BiCl₆]Cl·H₂O was used as catalyst to catalyze the reaction of enamide with hydrogen peroxide at room temperature β-Conjugated addition of keto acids.Through a series of single factor analysis experiments,the optimum reaction conditions were selected from the aspects of catalyst dosage,solvent and reaction equivalence ratio.Finally,it is proved that bismuth catalyst can be recycled in this reaction system.Under the optimal conditions,a series of diaryl alkane derivatives were obtained in a short time,and the products were characterized by MS,1H NMR,13C NMR and other means.