| Trauma is due to mechanical injury factors that affect the body’s tissues or organs,so that the integrity of the skin or mucous membrane of the injured part is destroyed and the mechanical damage that is deep in the tissue and the outside world.Trauma is one of the common diseases of dogs and cats.There are many clinical drugs for treating trauma,but there is little data for comparative analysis of the effects of these drugs.In order to analyze the four common clinical trauma drugs,Bailingjin Fangbai and Ointment,Baiduobang Mupirocin Ointment,Kangfuxin Liquid,Povidone Iodine Cream,through the mouse trauma model and clinical practice In part of the research,the therapeutic effects of the four trauma drugs are compared and analyzed.Finally,the most effective trauma drugs are selected for clinical use to achieve the effect of guiding clinical medication,improving the cure rate,and establishing a good doctor-patient relationship.The mouse trauma model is to cut a 1.5 × 0.2 cm wound on the back of the mouse,set up a blank control group and a drug test group,and observe the growth of the diseased tissue and the pathological changes of the tissue section on 5 d and 10 d,and compare the wound Recovery situation.The clinical practice study was an internship at Shilibao Store in Beijing Guanzhong Animal Hospital from March 2019 to February 2020,and collected dog and cat trauma cases in the hospital and its three branch hospitals,and comprehensively recorded their medical treatment to the outcome Situation,statistics of the incidence of dog and cat trauma in Chaoyang District,Beijing,and comparative analysis of the therapeutic effects of four trauma drugs.The record contains:basic animal information,trauma,medication,recovery,etc.The therapeutic effect can be judged by the content of exudate during wound healing,the moisturizing effect of the drug,the wound infection,the growth of granulation tissue,the time of skin engagement,the time of epithelial formation,the time of crusting,and the time of healing.The following conclusions were obtained through the mouse trauma model and clinical practice:1.Comparison of the therapeutic effect of mouse trauma model:Kangfuxin liquid group>Bailingjinfangbaiji cream>Povidone iodine cream>Baidubang mupirocin ointment>blank control group.2.A total of 85 dog and cat trauma cases were collected during the internship,including 66 bites,10 car accidents,and 9 other traumas;80 had a good prognosis,1 amputation,2 hind limb paralysis,and 2 deaths;67 dogs(78.82%),a total of 18 cases(21.18%)of cats;59 cases(69.41%)of cases with a wound length less than 2 cm;bite cases occur frequently in spring and autumn,and the number of males who have not castrated is the largest;car accident cases have no obvious The gender differences and seasonal differences are strong in randomness.3.Comparison of clinical case treatment effect:suture case treatment effect,povidone-iodine cream>Baidubang mupirocin ointment>Bailingjinfangbai and ointment>rehabilitation new solution;open treatment of fresh pollution wound treatment effect,rehabilitation New solution>Bailingjinfangbai and ointment>Povidone iodine cream>Baidubang mupirocin ointment;open treatment of infection wounds,Baidubang mupirocin ointment>Bailing gold mupirocin ointment>Bailing Jinfang ointment New solution>Povidone iodine cream. |