Analysis Of Clinical Diagnosis And Treatment Of Hyperlipidemic Acute Pancreatitis And Biliary Acute Pancreatitis

Objective:In this study,the clinical data of patients with biliary acute pancreatitis and hyperlipidemic acute pancreatitis were analyzed in order to clarify the characteristics of these two etiological pancreatitis,better guide clinical diagnosis and treatment decisions,and benefit patients.Methods:The clinical data of patients with hyperlipidemic acute pancreatitis(HLAP)and biliary acute pancreatitis(ABP)treated in our hospital from September 2018 to September 2020 were analyzed retrospectively,including sex and age,laboratory indexes,proportion of moderate severe acute pancreatitis,local and systemic complications,BISAP score and the number of SIRS cases.Use statistical software to deal with and compare and analyze.Results:The age of onset in HLAP group was lower than that in ABP group,the incidence of male patients in HLAP group was higher than that in ABP group,the proportion of diabetes in HLAP group was higher than that in ABP group,and the BMI in HLAP group was higher than that in ABP group.There was no significant difference in the average pain relief time between the two groups,P<0.05.The levels of serum(AMY),total bilirubin(TBil),direct bilirubin(DBil),ALT and Ca2+ were lower than those in ABP group.CRP,urea nitrogen(BUN),blood glucose(GLU),VLDL in HLAP group were higher than those in ABP group.There was no significant difference in serum lipase(LPS),cholesterol(TC)and high density lipoprotein(HDL)between the two groups,P>0.05.The proportion of moderate severe pancreatitis,the incidence of SIRS and the incidence of organ failure in HLAP group were significantly higher than those in ABP group(P<0.05).There was no significant difference in BISAP score and local complication incidence between the two groups,P>0.05.Conclusion: patients with hyperlipidemic acute pancreatitis tend to be younger,more male,more obese,and have a higher risk of diabetes,while biliary acute pancreatitis tends to occur in middle-aged and elderly female patients.The value of serum amylase in diagnosing hyperlipidemic acute pancreatitis and predicting the severity of acute pancreatitis is low.Hyperlipidemic acute pancreatitis should pay attention to long-term control of blood lipids and blood sugar,regulate diet and exercise,and biliary acute pancreatitis should pay attention to protecting the liver and promoting gallbladder.Compared with biliary acute pancreatitis,the proportion of patients with moderate severe acute pancreatitis,the incidence of SIRS and the incidence of organ failure are higher in hyperlipidemic acute pancreatitis than biliary acute pancreatitis,so the clinical development of hyperlipidemic acute pancreatitis should be paid more attention to.SIRS plays a strong predictive role in the deterioration of AP.Etiology(hyperlipidemia),obesity,CRP and triglyceride are independent risk factors for SIRS.