Effect Of Multimode Analgesia With Combination Of Preoperative TPVB And TPVB At The End Of The Operation In Patients Undergoing Single-port VATS

Objective:To investigate the effect of the combination of preoperative TPVB and TPVB at the end of the operation under ultrasound guidance with different concentrations of ropivacaine on perioperative analgesia and the incidence of adverse reactions in patients undergoing single-port VATS.Methods:According to the concentration of ropivacaine,60 patients undergoing single-port VATS were randomly divided into three groups by a random number table method:Group A(preoperative ropivacaine 0.4% 10 ml and at the end of the operation ropivacaine 0.4% 20ml);Group B(preoperative ropivacaine 0.4% 10 ml and at the end of the operation ropivacaine 0.25% 20ml);Group C(preoperative ropivacaine 0.4%10ml);The pressing times of PCIA,adverse reactions,VAS scores and rescue times were recorded at 6,12,24 h after the operation.Results:In research,there was no significant difference in general condition.Duration of surgery was also not statistically significant(P>0.05).At rest,Group A’s VAS scores were significantly lower than those in Group B at 6,12h;And those in Group B were lower than VAS scores in Group C at the same time;During movement,Group A’s VAS scores were lower those in Group B at 6 h;And those in Group B were lower than those in Group C at 6 h;There was no significant difference in VAS scores at 24 h.The pressing times of PCIA at three time points in Group A,B were significantly lower than those in Group C;And those at 6,12 h in Group A were also lower than those in Group B;The times of rescue analgesics in Group C were significantly higher than those in Group A,B in 24 h;Only the total incidence of adverse reactions in Group A were lower than those in Group C at 24 h(P<0.0167).Conclusion: Compared with the preoperative paravertebral nerve block,the combination of the preoperative TPVB and TPVB at the end of the operation is more effective.And the combination of TPVB can reduce the incidence of adverse reactions.