A Clinical Study Of Bushen Qufeng Decoction Combined With Acupuncture For The Treatment Of Renal Yang Deficient Ankylosing Spondylitis

Objective: To comprehensively evaluate the clinical symptoms,disease activity and pain degree of patients with ankylosing spondylitis due to deficiency of kidney-yang by Bushen Qufeng Decoction combined with acupuncture,and analyze its advantages,so as to provide an effective method for the treatment of this disease and provide reference for clinical popularization.Methods: Sixty-four patients who met the inclusion criteria were randomly divided into treatment group and control group,with 32 cases in each group.The control group was treated with oral sulfasalazine enteric-coated tablets combined with celecoxib capsules.The treatment group was treated with Bushen Qufeng Decoction combined with acupuncture on the basis of the control group,and the course of treatment was 12 weeks.The TCM syndrome scores and Bath Ankylosing Spondylitis Disease Activity Index(BASDAI)were recorded and collected before and after treatment.Bath ankylosing spondylitis functional index(BASFI);Pain visual analogue scale(VAS);ESR and C reactive protein(CRP).The statistical software SPSS26.0was used for statistical analysis to evaluate the clinical therapeutic effect of Bushen Qufeng Decoction combined with acupuncture on ankylosing spondylitis of kidney-yang deficiency type,and to record the occurrence of adverse reactions during the test.Results:(1)In terms of curative effect,after 12 weeks of treatment,the clinical curative effect of ASAS20 in the treatment group.The total effective rate was 87.50%,and the total effective rate of TCM syndrome was 87.50%.In the control group,the total effective rate of ASAS20 was 65.63%,and the total effective rate of TCM syndrome was 62.5%.There was significant difference between the two groups(P<0.05).(2)After treatment,the scores of BASDAI and BASFI in the two groups decreased compared with those before treatment,and the difference was statistically significant(P<0.01).The comparison of BASDAI and BASFI between the two groups showed that the treatment group was superior to the control group(P<0.01).(3)In terms of VAS scale scores,the overall VAS pain scores,back pain VAS scores and morning stiffness VAS scores of the two groups decreased after treatment,and the difference was statistically significant(P<0.01).(4)In the aspect of TCM syndrome integral,the main symptom integral,secondary symptom integral and total syndrome integral of the two groups were improved compared with those before treatment,and the difference was statistically significant(P<0.05),but the treatment group was superior to the control group(P<0.05).(5)In terms of laboratory examination,ESR and CRP of patients in the two groups were lower than before,and the difference was statistically significant(P<0.01).Compared with ESR and CRP between the two groups,the treatment group was superior to the control group(P<0.01).(6)There was no serious adverse events in the two groups during the treatment.Conclusions: 1.Bushen Qufeng Decoction combined with acupuncture therapy can obviously improve lumbosacral pain,morning stiffness and spinal function of ankylosing spondylitis patients with kidney-yang deficiency,and reduce erythrocyte sedimentation rate and C-reactive protein.The therapeutic effect is better than that of the control group only using sulfasalazine enteric-coated tablets combined with celecoxib capsules.2.The treatment of ankylosing spondylitis with kidney-yang deficiency by Bushen Qufeng Decoction combined with acupuncture can improve the clinical curative effect,while the incidence of adverse reactions is lower than that of the control group only using sulfasalazine enteric-coated tablets combined with celecoxib capsules,which indicates that the clinical safety is higher.