| Objective:By analyzing the effects of sex,age,body mass index and body surface area on the bone mineral density of lumbar vertebrae and hip in patients with type 2diabetes mellitus,the correlation between osteoporosis and osteoporosis was studied.in order to provide support for early prevention and diagnosis of osteoporosis in patients with type 2 diabetes mellitus.Methods:Total of 414 patients with type 2 diabetes treated in the first affiliated Hospital of Hainan Medical College from January 2017 to December 2019 were collected,including 127 males and 287 females.According to the value of bone mineral density(BMD),the osteoporosis group(OP)was divided into two groups:osteoporosis group(24 males and 140 females)and non-osteoporosis group(NOP group).The sex,age,height and weight were recorded,and the body mass index and body surface area were calculated and analyzed.All parameters are expressed by mean±standard deviation(?x±s).The relationship between age,sex,body mass index,body surface area and bone mineral density of different bone sites in patients with type 2 diabetes mellitus was analyzed by Pearson correlation analysis and multiple linear regression analysis.The related factors of osteoporosis in patients with type 2diabetes mellitus were analyzed by binary logistic regression analysis,and the constituent ratio of bone mineral density among different body surface area groups was compared by chi-square test or Fisher exact probability method(P<0.05).Results:1.There was a significant linear correlation between sex,body mass index(BMI),body surface area and bone mineral density(BMD)of femoral neck,greater trochanter,intertrochanteric,hip,L1-L4 vertebrae and total lumbar vertebrae in patients with type 2 diabetes mellitus(P<0.01).There was a significant linear correlation between age and bone mineral density of femoral neck,greater trochanter,intertrochanteric and hip in patients with type 2 diabetes mellitus.In patients with type 2 diabetes,the bone mineral density of men was significantly higher than that of women;the larger the body surface area,the greater the bone mineral density;with the increase of age,only the femoral neck,greater trochanter,intertrochanteric and hip bone mineral density decreased.2.There are three main related factors of type 2diabetes mellitus complicated with osteoporosis:age(P<0.001),sex(P<0.01),body surface area(P<0.015),and body mass index(BMI)is not related factor(P<0.389).3.The bone mineral density(BMD)constituent ratio of female patients with type 2 diabetes mellitus was significantly different among different body surface area groups(P<0.001).The incidence of osteoporosis in three individual surface area groups was from high to low:small body surface area group(68.6%)>medium body surface volume group(50.5%)>general surface area group(23.8%).The incidence of osteoporosis in the three individual surface area groups was from high to low:small body surface area group(68.6%)>medium body surface area group(50.5%)>general surface area group(23.8%).Conclusion:The BMD of femoral neck,greater trochanter,intertrochanteric,hip,L1-L4 and total lumbar vertebrae in patients with type 2 diabetes mellitus were decreased by female and corpuscle surface area.The main related factors of type 2diabetes mellitus complicated with osteoporosis were age,sex and body surface area,advanced age was the promoting factor,male and general surface area were protective factors.In female patients with type 2 diabetes,body surface area is an important factor that can not be ignored in patients with osteoporosis,patients with small body surface area and medium body surface area(that is,body surface area≤1.82m~2)should pay more attention to bone mineral density,need early diagnosis and prevention of osteoporosis to avoid the serious consequences of fracture. |
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