Clinical Study On Zishui Hehuan Pill In Treating Woman With Hypoactive Sexual Desire Disorder Of Kidney Deficiency And Liver Stagnation

ObjectiveCombining the clinical experience of the instructor for many years,through clinical research,observe the clinical efficacy of Zishui Hehuan Pill in treating libido in women with kidney deficiency and liver stagnation,and to explore its mechanism of action to verify the feasibility of treating female libido from liver and kidney.The further promotion and application of hydrazine pills provide a clinical basis.MethodsIn this study,70 patients who met the inclusion criteria were randomly assigned to the observation group and the control group.The two groups were given psychosocial treatment,mainly cognitive behavioral therapy(CBT)and self-help education(reading therapy).The observation group took Zishui Hehuan pill orally on the basis of CBT,while the control group took placebo pill orally for 4 weeks.The total scores of TCM symptoms and individual symptom scores,SIDI-F total scores and individual item scores,and sex hormones were recorded before and after treatment,and the safety of each patient was observed.Data analysis was performed using SPSS 24.0.Results1.Comparison of total scores of TCM syndromes:Both groups of treatments can improve the symptoms of kidney deficiency and liver stagnation,and the observation group is superior to the control group.2.Comparison of single symptom scores of TCM:Both groups can improve low libido,depression,irritability,palpitations,and abdominal pain,and the observation group is superior to the control group;in relieving the patient’s waist and knees,dizziness and tinnitus There was a statistic ally significant difference between the observation group and the pre-treatment group(P<0.05),but there was no significant difference between the control group and the control group(P>0.05).There was no significant difference in the improvement of patients’ forgetfulness between the two groups(P>0.05).3.Comparison of TCM syndrome efficacy:The total effective rate of the observation group was 82.86%,and the total effective rate of the contr ol group was 48.57%,indicating that the effect of improving the TCM symp toms in the observation group was significantly better than that of the control group.4.SIDI-F total score comparison:Both groups of treatment can alleviate the pain of libido,and the observation group is superior to the control group.5.SIDI-F single item comparison:both groups of treatment can improve sexual relationship,distress,positive thoughts,arousal frequency,and the observation group is better than the control group;in the initiative to improve the desire,emotional embarrassment.There was a significant difference in the duration of treatment and orgasm in the observation group(P<0.01).There was no significant difference in the control group after treatment(P>0.05).There were no significant differences between the two groups after treatment(P>0.05)in terms of patient acceptance,frequency of demand,satisfaction of demand,and yellow books.6.Comparison of female sex hormones:After treatment,the testosterone and estradiol in the observation group were significantly different from those before treatment(P<0.05),but there was no significant difference in P,PRL,LH and FSH before treatment(P>0.05);there were no significant differences in the sex hormones between the six groups before and after treatment(P>0.05).7.Safety evaluation:During the clinical observation process,there were no abnormalities in the safety indicators before and after treatment,and no obvious adverse reactions were observed.Conclusions1.Zishui Hehuan Pill combined with psychosocial adjuvant therapy can regulate the endocrine of women of childbearing age,improve the level of estrogen and testosterone,and improve female sexual desire decline.2.Zishui Hehuan Pill can reduce the TCM syndrome score and SIDI-F score,improve the clinical symptoms of patients and improve the quality of life of patients.3.It is effective and feasible to treat female libido from the treatment of liver and kidney.4.Zishui Hehuan Pills did not show obvious adverse reactions during the clinical research process,and it was convenient to take,reliable in efficacy,and has broad clinical application prospects,which deserves further promotion.