| Objective: In the process of clinical treatment of lumbar disc herniation,taking patients with acute stage of cold-dampness type lumbar disc herniation as the research object,to observe the change degree of pain visual analogue scale(VAS)score,JOA score assessed by Japan Orthopedics Association and the determination of JOA score efficacy standard before and after the treatment of the disease by external application of Xiaotonglishui compound plaster combined with etoricoxib tablet and during follow-up,and to explore the therapeutic effect of Xiaotonglishui compound plaster combined with etoricoxib tablet on acute stage of cold-dampness type lumbar disc herniation.Methods: 60 patients with acute stage of cold-dampness type lumbar disc herniation admitted to Henan Provincial Hospital of Traditional Chinese Medicine from January2018 to January 2019 were selected.All patients met the diagnostic criteria of lumbar disc herniation and the dialectical criteria of cold-dampness type of traditional Chinese medicine.According to the patient’s visiting order and combined with the random number table,the patients were equally divided into observation group and treatment group with 30 cases in each group.The observation group: 18 males and 12 females,aged 22-58(36.23±8.50)years,course of disease 1-6(3.43±1.41)days,VAS score before treatment 6.93±1.26,JOA score before treatment 10.93±1.79;Control group:16 males and 14 females,aged 21-59(35.40±9.71)years,course of disease 1-6(3.60±1.35)days,VAS score 6.77±1.36 before treatment,JOA score 10.90±1.58 before treatment.There was no significant difference between the two groups in general data such as gender,age,course of disease,VAS score and JOA score before treatment(p>0.05),which was comparable.The observation group was given external application of Xiaotong plaster,and the control group was given external application of Qizheng Xiaotong plaster and oral application of etoricoxib tablet.Patients were instructed tostay in bed and avoid physical labor between the two groups.During the treatment,adverse drug reactions of patients were monitored,and VAS scores and JOA scores of patients in each group were observed and recorded after 2 weeks of treatment and 1month after treatment respectively,and the data of each group were compared accordingly to draw a conclusion.Results: After 2 weeks of treatment,the VAS score in the observation group was 2.47±1.38,while that in the control group was 2.80±1.63.There was no statistical significance between the two groups(p>0.05).The scores before and after treatment in the two groups were compared respectively(p<0.05),which had statistical significance.One month after treatment,the VAS score of the observation group was 2.57±1.36,while that of the control group was 3.67±1.56.Compared with the two groups,p<0.05 was statistically significant.Compared within the observation group and one month after treatment,p>0.05 was not statistically significant.Compared within the control group and one month after treatment,p<0.05 was statistically significant.After 2weeks of treatment,the JOA score in the observation group was 21.73±2.96,while that in the control group was 21.27±2.84.There was no statistical significance between the two groups(p>0.05).The scores before and after treatment in the two groups were compared respectively(p<0.05),which had statistical significance.One month after treatment,the JOA score in the observation group was 21.47±3.34,while that in the control group was 19.20±2.50.Compared with the two groups,p<0.05 was statistically significant.Compared with the observation group after treatment and one month after treatment,p>0.05 was not statistically significant.Compared with the control group after treatment and one month after treatment,p>0.05 was statistically significant.After treatment,the apparent efficiency of the observation group was 86.66%,that of the control group was 80.00%,and that of the observation group was 76.67% and that of the control group was 43.33% one month after treatment.Adverse drug reactions: There were no abnormalities of blood routine,liver function and renal function in both groups during and after treatment.No skin allergy such as red rash and swelling occurred in the observation group during the treatment period;1 person experienced gastrointestinal reactions such as nausea and vomiting during the treatment period;1 person experienced skin allergy such as red rash and 1person experienced gastrointestinal reactions such as nausea and vomiting during the treatment period in the treatment group.Conclusion: 1.Xiaotong Lishui patch combined with etoricoxib tablet and QizhengXiaotong patch combined with etoricoxib tablet can effectively relieve lumbago and lower limb radiation pain symptoms in acute stage of cold-dampness lumbar disc herniation.However,in terms of long-term analgesic effect of drugs,Xiaotong Lishui compound patch has better effect and this group is superior to the latter in terms of adverse drug reactions,i.e.safety.2.Xiaotong Lishui patch combined with etoricoxib tablet and Qizheng Xiaoshui patch combined with etoricoxib tablet can effectively improve patients’ JOA score and lumbar function in the treatment of acute stage of cold-dampness type lumbar disc herniation,but in terms of long-term efficacy,Xiaotong Lishui patch combined with etoricoxib tablet treatment scheme is more advantageous.3.Compared with Qizheng Xiaotong Patch,Xiaotong Lishui Patch has less adverse drug reactions and less skin irritation. |
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