Effect Of Qilian Xiaoke On Abdominal Visceral Fat Content And Serum Chemerin Level In Overweight/Obesity Type 2 Diabetic Patients

Objective: The Qilian Xiaoke Recipe was applied to overweight/obese T2 DM patients to observe the effect of Qilian Xiaoke Recipe on abdominal visceral fat content and serum chemerin level,so as to confirm the exact effect of traditional Chinese medicine on overweight/obese T2 DM treatment.Methods: Collected patients from the Department of Endocrinology and Metabolism of the Affiliated Hospital of Changchun University of Traditional Chinese Medicine and the treatment area,and randomly divided 72 patients into the treatment group,36 cases in the treatment group and 36 cases in the control group,for diabetes education,related knowledge popularization and the same lifestyle Instructed,the treatment group was given Qilian Xiaoke Recipe(300ml decoction to extract the juice,divided into the morning and evening),and the control group was given metformin hydrochloride tablets(0.85 g,once a day with meals),4weeks as a course of treatment.Carry out 3 courses of system diagnosis and treatment.Before and after treatment,the patients were checked for TCM symptom score,visceral fat content,serum Chemerin,fasting blood glucose,2-hour postprandial blood glucose,glycosylated hemoglobin,total cholesterol,triglycerides,BMI,WC and WHR,and observed The physical and chemical examination changes of the two groups of patients before and after treatment,after statistical analysis,the efficacy and safety evaluation were obtained.Result:1.After 12 weeks of treatment,the total effective rate in the treatment group was 85.3%,and the total effective rate in the control group was 65.6%.There was a significant difference between the two groups(P<0.05).2.In terms of improving the symptoms of TCM,the treatment group can effectively improve chest abdominal distension,heaviness of the limbs,nausea and vomiting,fatigue,fatigue,abnormal sweating,thirst and low drinking,dizziness,yellow urine and uncomfortable stools.Group had better curative effect(P <0.05).In terms of physical and chemical examinations,FPG,2-hour postprandial blood glucose,Hb Alc,triglycerides,total cholesterol,visceral fat,and serum Chemerin in the two groups after treatment were significantly lower than before treatment,which was statistically significant(P<0.05);There was no statistically significant difference between the inspections of the latter two groups(P >0.05).In terms of anthropometric indicators,the body mass index,waist circumference,and waist-to-hip ratio of the two groups after treatment were significantly lower than those before treatment,which was statistically significant(P <0.05);after treatment,there was no statistically significant difference between the two groups of indicators(P > 0.05).3.In terms of safety,there was no abnormality in the two groups before and after treatment.Conclusion: In the process of treating overweight/obese T2 DM,Qilian Xiaoke Decoction can effectively improve the symptoms of Chinese medicine,make the visceral fat content and serum Chemerin show a downward trend,at the same time,it can reduce blood sugar,blood lipids,weight loss,and regulate glucose and lipid metabolism disorders.It is equivalent,and there are no adverse reactions and side effects during the treatment process,and the safety factor is high.It is recommended that the majority of clinicians use it reasonably.