The Predictive Value Of PLR In Ventricular Remodeling After PCI In Patients With Acute Coronary Syndrome

Objective:To evaluate the value of platelet and lymphocyte ratio as a new prognostic factor in predicting ventricular remodeling after percutaneous coronary intervention for acute coronary syndrome which is a common cardiovascular disease.Methods:From November 1,2018 to May 31,2020 in jilin province people’s hospital of the first time to Percutaneous coronary intervention in patients with acute coronary syndrome as the research object,select the number of cases of 68 patients,statistical patients basic information on admission to hospital: name,sex,age,disease time,disease types,past history of hypertension and diabetes mellitus,past medical history of smoking and drinking,on platelet and lymphocyte,neutrophil count,triglyceride and cholesterol levels on admission,the relevant indicators of cardiac color ultrasound on admission.Among 6 to 12 months after discharge and admission,the relevant indicators of cardiac color ultrasound before the patient is admitted.NLR value was calculated based on neutrophil count and lymphocyte count at admission,and PLR value was calculated based on platelet and lymphocyte count.The optimal PLR value was obtained by drawing ROC curve and calculating Youden index.The patients were divided into two groups: the high PLR group(30 cases,PLR > 219)and the low PLR group(38 cases,PLR < 219).The left ventricular end-diastolic volume growth rate(ΔLVEDV)was calculated according to the patient’s left ventricular end-diastolic volume(LVEDV)reviewed after admission and discharge.If the value is over 20%,it indicates that left ventricular remodeling has occurred.According to the statistical data of patients,the statistical relationship between the high PLR group and the low PLR group was compared,as well as the predictive value of NLR and PLR in left ventricular remodeling,so as to analyze the relationship between PLR and ventricular remodeling in patients with acute coronary syndrome after PCI.Results:Statistical analysis showed that there were no significant differences in age,gender and disease time between the high and low PLR groups(P > 0.05).There was no significant difference in the number of patients with different disease types between the two groups(P > 0.05).However,there were significant statistical differences in the number of smoking,drinking,hypertension and diabetes patients between the two groups(P<0.05).There were significant statistical differences in the results of reexamination and admission examination between the two groups of heart color ultrasound(P < 0.05),and the difference between the two examinations was greater in the high PLR group.According to the calculated values,the ROC curve showed that both NLR and PLR had predictive value for left ventricular remodeling in patients with acute coronary syndrome after PCI,but PLR had better predictive value for left ventricular remodeling than NLR(P<0.05).Logistic regression analysis showed that previous smoking and drinking history,hypertension and diabetes were risk factors for ventricular remodeling after PCI.According to Pearson correlation analysis,PLR was positively correlated with triglyceride and cholesterol levels.Conclusion: Both NLR and PLR have predictive value in ventricular remodeling after PCI,but PLR has a good predictive value for left ventricular remodeling in patients with acute coronary syndrome after PCI,which is suitable for clinical application.Previous smoking and drinking history,history of hypertension and history of diabetes are independent risk factors for the occurrence of left ventricular remodeling in patients with acute coronary syndrome;and the elevation of blood lipid has a certain correlation with the occurrence of ventricular remodeling,which should be controlled from the source to reduce the risk of remodeling.