| Objective: According to detect the levels of white blood cells(WBC),C-reactive protein(CRP)and serum cholinesterase(Ch E)in patients with different PSI scores before admission and after treatment,the relationship between the various indicators and the severity of elderly lung infections It also points out that serum cholinesterase can be used as a new indicator to assess the severity of elderly patients with lung infection.Methods: This article collected 58 elderly patients with lung infection who were ≥65years old who were admitted to the relevant departments of our hospital from September2018 to December 2020,and collected 18 elderly patients who had a physical examination in our hospital during the same period of time and had no recent infections.As a control group.According to the PSI score,the diagnosed elderly patients with lung infection were divided into three groups: PSI score Ⅰ~Ⅲ,PSI score Ⅳ,and PSI score Ⅴ.The gender,age,length of hospital stay,time of admission and time of admission of the three groups of observation groups were collected.The blood WBC count,blood CRP and serum Ch E level rechecked after treatment,the gender,age,blood WBC count,blood CRP and serum Ch E level of the control group.Use statistical methods to analyze the blood WBC counts,blood CRP and serum Ch E levels of subjects in the observation group upon admission and after treatment and patients with different prognosis,and analyze the blood WBC counts,blood CRP and blood levels through correlation analysis The relationship between CHE and PSI ratings.Results: According to the gender and age of the selected patients and the length of stay in the observation group,the blood WBC counts,blood CRP and serum Ch E levels were compared between the control group and the observation group when they were admitted to the hospital and after treatment improved.The blood WBC counts,blood WBC counts,Correlation analysis of blood CRP and serum Ch E with PSI scoring grades obtained:1.There was no significant difference in gender comparison between the control group and the three observation groups(P>0.05).2.There are differences in the age of patients between the control group and the three bservation groups(P<0.05).3.There are significant differences in the length of stay in the three observation groups(P<0.05).4.There were significant differences in blood WBC counts,blood CRP and serum Ch E levels between the control group and the observation group when they were admitted to the hospital(P<0.05).5.There were significant differences in the levels of white blood cells,CRP,and Ch E in the three observation groups before admission and after treatment(P<0.05).6.In the correlation analysis,the PSI scoring level is positively correlated with WBC and CRP,and the PSI scoring level is negatively correlated with the Ch E level,and the difference is statistically significant.(P<0.001)Conclusion:1.Although the white blood cell count is a classic indicator for judging the severity of infection,due to the influence of many factors,it is not possible to simply rely on its changes to assess the severity of lung infection.2.Although CRP showed changes before and after treatment in this study,and was positively correlated with the PSI score,indicating that it can be used as an auxiliary method to judge the severity of lung infections in the elderly,but due to its long half-life or combined with other non-bacterial pathogen infections And so on,it is impossible to determine its relationship with the severity of elderly lung infections.3.Serum cholinesterase is less affected by other factors in judging the severity of lung infection in the elderly,and its indicators change significantly before and after treatment,and are negatively correlated with the PSI score,indicating that serum Ch E is to a certain extent It can reflect the severity and prognosis of elderly patients with lung infection. |