| ObjectiveEndometriosis is known as EM.It is a disease caused by the growth of endometrial tissue outside the uterine cativy.It is common disease of gynecology and obstetrics,which is a typical chronic disease.The incidence rate of EM in women of child-bearing period is as high as 10%to 15%[1],and shows an increasing trend year by year.The Age of Onset is getting younger and younger.Although most of the EM is benign,there is a risk of malignant transformation[2][3].The extra pathogenesis is not clear,and the main clinical theories include Cultivation theory,induction theory,EM determination theory and coelomic metaplasia theory etc.Studies have reported that young age of menarchy,long menstrual period,fewer pregnancies,uterine abnormalities,oral contraceptives,uterine operation history,family history of EM,dioxins are high risk factors[4][5][6][7].EM that leads to menstrual pain and long-term pelvic ache,infertility,complex pelvic adhesion and mass etc,is characterized by extensive lesions,diverse forms,high invasiveness,high recurrence rate after treatment,and poor overall therapeutic effect.EM,known as benign cancer,leads to prolonged body and mind pain,seriously reducing the living standard.Timely prevention,diagnosis,remedy,administration and management of EM and improvement of patient’s living standard of life is an urgent clinical difficulty.With the transformation of medical model and life stress,people begin to keep a watchful eye on the influence of mental factors on various aspects of disease.Personality is a core vocabulary of psychology.Many studies have shown that there is a very close relationship between personality and diseases:people with certain personality characteristics may have an increased risk of suffering from certain diseases.Therefore,to study the distribution characteristics of EM personality and the correlation between EM personality and TCM syndromes is of important influence on the prevention and cure of EM.symptom questionnaire of TCM was designed and developed by our research team,and has been used in clinical studies for many times.By investigating the demographic data,"Five-pattern Personality" and symptom questionnaire of TCM of patients with EM,we explored the "Five-pattern Personality" distribution regularity and relationship between "Five-pattern Personality" andTCM syndromes in EM patients.The study hammer at pro viding a academic basis and guidance at prevention and cure of EM from the aspect of Psychology of traditional Chinese medicine.We are committed to enrich the content of syndrome differentiation and treatment.We apply oneself to boost clinical efficacy.MethodThis study adopts the method of questionnaire investigation.200 patients with EM diagnosed clinically or surgically were selected from October,2017toDecember,2018inthe gynecological apartmentofGAMH.The patient fillsthegeneral information,"Five-pattern Personality" test and symptom record of TCM inindependently and voluntary inaquiet and unaffected environment.Conduct training for researchers on relevant knowledge of questionnaire and instructions on matters needing attention in filling.Tables that do not meet the valid criteria of the questionnaire-will be excluded strictly.The original data were checked by two people and were input into the clinical research data sharing system of GAMH.Through the system,the firsthand data of patients is analyzed,extracted,preprocessed by the platform,and then respectively summarized into Excel format for output.The statistical software used was SPSS21.0.Demographic data use Descriptive statistical analysis.Quantitative data is going to be the mean and the standard deviation.Qualitative data are expressed in terms offrequency.Classified datawereprocessed withK-means.Quantitative data accord with normal distribution and independent sample T-test is used.For the comparison of quantitative data and qualitative data,One-way ANOVA was used(the variances were homogeneous),and non-parametric test was used(the variances were heterogeneous).P<0.05 was the significant criterion.Result1 General larithmics data:The age range case of the patients included in this study ranged from 19 to 56 years old.The average age is(33.8±5.93)years old.The age were mainly distributed between 25 yearsold(inclusive)and 45 yearsold(inclusive)(171patients,94.05%);There are 6 people who are under 25 years old,accountingfor3.30%;There are 5 people who are older 45 years,accounting for 2.75%.The marital status of the patients included in this stud y was mainly married(134 patients,73.63%);divorced(2 patients,1.09%);unmarried with sexual life(23 patients,12.64%);unmarried without sexual life(23 patients,12.64%).The education status of the patients included in this study was mainly bachelor degree or above(139patients,76.36%);seniorhighschool to college degree school(42patients,23.08%);juniormiddle school or below(1 patient,0.55%).The career status ofthepatients includedinthisstudy wasmainly mentalwork(158patients,86.81%);physical work(8patients,4.40%)and the unemployed(16 patients,8.79%).The most common reason for patients to seek medical treament is the discovery of ultrasound abnormality(96 patients,52.75%);infertility(18 patients,9.89%)secondary dysmenorrhea(53 patients,29.12%);pelvic pain(4 patients,2.20%);secondary dysmenorrhea with pelvic pain(5 patients.2.75%);secondary dysmenorrhea with infertility(6 patients.3.30%).2 The distribution of "Five-pattern Personality":Compared with the countrywide norm for women."Five-pattern Personality" of EM patients in this study had significantly lower scores in "Taiyang""shaoyange" Yinyangheping""Shaoyin" four dimensions.and significantly higher scores in the "Taiyin".There are statistical differences in all five dimensions(P<0.05).The obvious personality characteristics of the "Taiyin" dimension are modesty in appearance,suspicious in mind,thoughtful.meet things with a pessimistic and disappoint attitude,timid,feminine and indecisive,keeping a certain distance from others,unwilling to contact people,refusing to interact with people,not interested in exciting things,conservative,selfish,determined by the success or failureofothersfirst.and notwillingto takethelead.Poor "Taiyang" shaoyang "Yinyangheping""Shaoyin" poorfour dimensions means that patient poor ability toreact to things、poor vigilance、poor flexibility、poor balance and poor tendency.They are not being able to handle life’s problem properly.They cannot reasonably channel bad emotion.they are unable to control their mindset,aggravating the "Tai yin" dimension of introversion,pessimism,conservatism and anxiety.There was no statistical significance in the comparison of ""Five-pattern Personality""among EM patients of different ages and educational levels.3 Distribution of TCM syndromes:K-means cluster method was used.Throug hthe clustering of symptomitems,182patientswere splitinto two-seven categories(The number of iterations is 10,and the convergence criterion is 0).and the results showed that when divided into four kinds,,the symptoms and signs had good dispersion,and the symptom distribution was clear,which was consistent with both the theory of traditional Chinese medicine and the clinical practice.By analyzingthe difference of clinical symptoms among the categories,referring to "Chinese Clinical Diagnosis and Treatment Terms Symptoms" and combining with expert opinions.the first type is Qi stagnation and blood stasis syndrome;the second kind is kidney deficiency and blood stasis syndrome;the third typeis phlegm-dampness and blood stasis syndrome;thefourthtype isQi deficiency and blood stasis syndrome.65 patients of which are Qi stagnation and blood stasis syndrome.accountingfor35.7%:50patientsare Qi deficiency andblood stasissyndrome.accounting for27.5%;36 patients are kidney deficiency and blood stasis syndrome,accounting for 19.8%;31 patients are phlegm-dampness and blood stasis syndrome,accounting for 17.0%.Qi stagnationand bloodstasis syndrome is the most familiar syndrome type.4 The distribution of’Five-pattern Personality"of each syndrome:Compared withthenational female nonn,the scores ofthe Patients offour syndromes in the two dimensions of "Taiyang"、"Shaoyin" were lower than that of the national norm for women;the scores of the four syndromes in the dimensions of "Taiyin" were higher than thatof the national norm for women:all of them were statistically significant(P<0.05).The scores of the Patients of which are Qi stagnation and blood stasis syndrome in the dimension of "Shaoyang" dimension also was lower than thatofthenational femalenorm.The differences of three dimensionswere statistically significant(P<0.05).The scores of the Patients of which are Qi deficiency and blood stasis syndrome in the dimension of "Yin yangheping" dimension also was lower than that of the national female norm.The differences were statistically significant(P<0.05).Comparison results of ""Five-pattern Personality" "ofeachsyndromeinpatients with EM:there werestatistical differences in the scores of "Taiyin" dimension ofthe four syndrome types(P<0.05),and thenpair-to-pair comparisonbetweenthe groups showed that the scores of the EM patients with Qi deficiency and blood stasis syndrome in "Taiyin" dimension was lower than that of the EM patients with Qi stagnation and blood stasis syndrome andkidney deficiency and blood stasis syndrome.ConclusionEM patients have obvious tendencies in the "Five-pattern Personality":significant "Taiyin"dimension,poof "Taiyang" "shaoyang" "Yinyangheping" and "Shaoyin" dimensions;comparison results of ""Five-pattern Personality" "of each syndrome in patients with EM show that the scores of the EM patients with Qi deficiency and blood stasis syndrome in "Taiyin" dimension was lower than that of the EM patients with Qi stagnation and blood stasis syndrome and kidney deficiency and blood stasis syndrome.It suggests that "Five-pattern Personality" has certain influence on the occurrence and development of EM."Five-pattern Personality" has little influence on syndrome distribution.On the basis of dialectical treatment,clinical treatment should pay attention to the psychological state of patients.According to the personality characteristics of the patients,the "state" treatment was carried out,and the components of Yin and Yang were adjusted with purpose.To help them adopt corresponding dietary habits and exercise types in their daily life,so as so further improve the clinical efficacy. |
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