| ObjectiveUse the NRS2002 scale for nutritional risk screening for hospitalized patients with acute myeloid leukemia,understand the role of the NRS2002 scale in hospitalized patients with acute myeloid leukemia,explore the impact of nutrition on chemotherapy complications in patients with acute myeloid leukemia,and provide patients with personalized nutrition support programs in accordance with.MethodsSelect patients with complete morphological remission after chemotherapy for acute myeloid leukemia admitted to the Department of Hematology,Affiliated Hospital of Binzhou Medical College from January 1,2019 to December 31,2019.NRS2002 nutritional screening will be performed within 24 hours of admission,and the patients will be divided into There are nutritional risk group and non-nutrition risk group,and the two groups of patients are divided into control group and intervention group by random number table method.Observe and compare the body weight,BMI,total serum protein,albumin,duration of agranulocytosis,platelet recovery time,minimum hemoglobin,platelet number,red blood cell transfusion,and side effects of chemotherapy(nausea,vomiting,diarrhea),Mucositis),length of stay,etc.Results171 patients who met the criteria were included,46 patients in the nutrition risk intervention group,41 patients in the control group,43 patients in the non-nutrition risk intervention group,and 41 patients in the control group.(1)The difference in weight and BMI of patients without nutritional risk is significantly smaller than that of patients with nutritional risk(P<0.001),and the difference of patients with nutritional risk is significantly reduced after nutrition intervention(P<0.001).There was a difference in the difference in body weight and BMI between the non-nutrition risk intervention group and the control group,but the difference between the two was not statistically significant(P>0.05).(2)The serum albumin and total protein levels of the four groups of patients showed a general downward trend,and the levels of serum albumin and total protein of the patients without nutritional risk decreased to a lesser extent.Among the four groups of patients,the serum albumin and The average level of total protein was higher than that of the two control groups,and the difference between the intervention groups was smaller than that of the control group.The average and minimum values of albumin and total protein in patients with nutritional risk intervention groups were significantly different from those in the control group.(P<0.001);The average,minimum,and difference of albumin and total protein in the non-nutrition-risk control group patients were significantly different from those in the nutrition-risk control group(P<0.001).(3)The incidence and severity of nausea,vomiting,diarrhea,oral mucositis in the non-nutrition risk group were lower than those in the nutritional risk group(P<0.001).The severity was significantly lower than that in the control group(P<0.001).The incidence and severity of complications after nutritional intervention in patients without nutritional risk were lower than those in the control group,but the difference was not statistically significant(P>0.05).(4)During the bone marrow suppression period after chemotherapy,after different nutrition intervention methods were used,the duration of granulosa deficiency and platelet recovery time in the two groups with nutritional risk were longer than those in the two groups without nutritional risk;the number of suspended red blood cells and platelets was transfused.In terms of nutritional risk,there were more patients in the two groups with nutritional risk than those without nutritional risk,and the minimum hemoglobin value in patients without nutritional risk was higher than that in patients with nutritional risk,but the differences were not statistically significant(P>0.05);interventions with nutritional risk The hematological parameters of the patients in the group were better than those in the control group,but the difference was not statistically significant(P>0.05).(5)The patients in the control group with nutritional risk had longer hospital stays than the patients without the control group with nutritional risk,and the difference was statistically significant(P<0.05);after nutritional intervention,patients with nutritional risk shortened the hospitalization time(P<0.05)There was no significant difference between the control group and the non-nutrition risk group(P>0.05).Conclusion1.Individualized nutritional support can improve the nutritional status of patients with acute leukemia chemotherapy;2.Individualized nutritional support can reduce the incidence of adverse reactions to chemotherapy in patients with acute myeloid leukemia;3.Individualized nutritional support can shorten the length of hospitalization for patients with acute myeloid leukemia chemotherapy;4.NRS2002 has guiding significance for nutrition intervention in patients with acute myeloid leukemia chemotherapy. |
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