Analysis Of Clinical Characteristics And Outcomes Of In-hospital Adult Cardiac Arrest And Resuscitation Patients

Objective:To explore the clinical characteristics and outcomes of In-hospital adult cardiac arrest and resuscitation patients.Methods:To retrospectively collect clinical data of in-hospital adult cardiac arrest patients from October 1,2019 to September 30,2020,including general patient data,CA-related conditions and rescue data,outcome data,relevant time data.The main outcome indicator is the ROSC rate and 30-day survival rate after CA.Finally,through statistical analysis and comparison,the clinical characteristics of in-hospital adult cardiac arrest patients were analyzed,and the factors affecting ROSC and30-day survival after CA were summarized.Results:(1)A total of 308 patients were included in the study.Among them,males(219cases): females(89 cases)= 2.46,the age range is 18-102 years old,with an average of(64.02±15.38)years old,192 cases(62.3%)≥ 60 years old,mainly males and the elderly.The ROSC rate was 53.9%(166 cases),the CPC score was 1(1～1.75)30-day after CA,and the good prognosis rate of neurological function(CPC score 1～2)is 5.6%(17 cases).The ratio of patients with good neurological prognosis and survivors30-day after CA was 85%.251 patients had at least one underlying disease(81.5%),154 patients had two or more underlying diseases(50%),and 57 patients had no previous medical history except for this disease(18.5%),The main cause of CA is non-cardiogenic.The main location of CA is in the intensive care unit.The ROSC rate in emergency and intensive care units is higher than that of non-spontaneous circulation,and the heart rhythm during cardiac arrest is dominated by non-defibrillating heart rhythm.(2)Univariate analysis results: the comparison between the ROSC group and the non-return of spontaneous circulation group showed that there were statistically significant differences in the cause of CA,the location of CA,the interval between CPR and ROSC,the establishment of high-grade airway,the adrenaline administration rate(mg/min),the use of other resuscitation drugs.The comparison between the 30-day survival group after CA and the 30-day death group after CA showed that there were statistically significant differences in the season of CA,the interval from CPR to ROSC,the heart rhythm during CA,the use of blood pressure drugs,the use of other resuscitation drugs,and electrical defibrillation..(3)Multivariate logistic regression analysis showed that: ROSC group and non-ROSC group: the long interval between CPR and ROSC and the failure to establish a high-grade airway are risk factors for ROSC.Between the 30-day survival group after CA and the 30-day death group after CA: the need to use other resuscitation drugs and the long interval between CPR and ROSC are risk factors for30-day survival after CA,and defibrillating heart rhythm is a protective factor for30-day survival after CA.Conclusions:(1)Cardiac arrest is more common in adult males than women in hospitals.The elderly are more common.The ROSC rate is 53.9%,the 30-day survival rate after CA is 6.5%,and the good neurological prognosis rate 30-day after CA is 5.6%.The cause of CA is mostly non-cardiogenic.Among them,the intensive care unit has the highest incidence.The heart rhythm during CA is mainly non-defibrillating.(2)The long interval between CPR and ROSC and failure to establish a high-grade airway may reduce the ROSC rate.Defibrillating heart rhythm in CA can improve the survival rate of 30-day after CA.The need to use other resuscitation drugs and the long interval between CPR and ROSC is not conducive to survive30-day after CA..