| Objective: To evaluate the efficacy and safety of transcranial repetitive acupuncture stimulation therapy in the treatment of limb motor dysfunction in the acute phase of ischemic stroke,and to find the best program for acute ischemic stroke.To quantify acupuncture deqi sensation and reveal the potential association of acupuncture deqi sensation in improving limb motor dysfunction in the acute phase of ischemic stroke.Methods:1.Case selection: 60 patients in the acute phase of ischemic stroke who met the inclusion criteria and exclusion criteria of this topic were randomly divided into treatment group(n=30)and control group(n=30).2.basic treatment: the basic drug treatment of the three groups of patients were based on the "Chinese Guidelines for the Prevention and Treatment of Cerebrovascular Disease" program to control blood pressure,blood glucose,defibrination,lipid-lowering,anti-free radical nutrition of cranial nerves and symptomatic treatment,prevention and treatment of complications;hemiplegic limb rehabilitation basic treatment;limb function therapy instrument basic treatment;massage therapy.3.Treatment methods: The treatment group was given transcranial repeated acupuncture stimulation therapy after conventional scalp acupuncture and body acupuncture(high-frequency twisting manipulation was applied after acupuncture for deqi,and the needle rotation speed was required to reach more than 200 r/min and last for 3 ～ 5 min,followed by twisting once after 30 min).The control group was treated with simple conventional scalp acupuncture and body acupuncture(no manipulation was applied after acupuncture).Two groups of patients were treated with electroacupuncture after acupuncture and manipulation,using dense waves(frequency 5 to 10 HZ),the time was 30 minutes,twice a day.4.Course of treatment: In this experiment,each group was treated for 6days as a course of treatment,with 2 times a day and 1 day of rest every 6days,for a total of 4 courses of treatment.5.Efficacy evaluation: The corresponding neurological function rating scales of each group of patients before and after treatment include: myometry standard evaluation(MMT),neurological deficit score(NIHSS),activities of daily living score(Barthel index)and stroke diagnosis and efficacy evaluation after treatment.Three minutes after the end of the first acupuncture for each group of patients,a questionnaire survey of deqi sensation was conducted.6.statistical methods: SPSS 20.0 statistical software was used for statistical analysis of all data in the trial.Measurement data were expressed as mean±standard deviation(x±s),paired t-test was used for comparison of mean;paired t-test was used for comparison before and after treatment;rank sum test was used for comparison of clinical efficacy and muscle strength.Quantitative data of deqi were analyzed by logistic regression analysis to analyze the association between gender,age,disease duration,and deqi sensation and MMT muscle strength,NIHSS score,and Barthel index.Results:1.Comparison: There were significant differences in muscle strength rating,NIHSS score and Barthel index score after treatment in the treatment control group(P < 0.05).The values of muscle strength rating and Barthel index in the treatment group were significantly higher than those in the control group after treatment;the NIHSS score in the treatment group was significantly lower than that in the control group after treatment(P < 0.05).2.Intra-group comparison: There were significant differences in muscle strength rating,NIHSS score and Barthel index score between the control group and the control group after treatment(P < 0.05).3.Logistic regression analysis: After treatment,when the quantification of qi sensation was used as the independent variable and the lower limb free-hand muscle strength assessment(MMT),NIHSS score and Barthel index were used as the dependent variables,the differences were statistically significant(P < 0.05).4.Statistics of effective rate: After treatment,the overall response rate of the control group was 65.52%,the treatment response rate was 86.67%,the difference in the effective rate between the two groups was statistically significant(P < 0.05)Conclusion:1.Transcranial repetitive acupuncture stimulation therapy "and traditional acupuncture therapy have a definite effect on improving the rehabilitation of motor function in acute ischemic stroke,and good safety.2.The therapeutic effect of transcranial repeated acupuncture stimulation therapy on the basis of traditional scalp acupuncture combined with body acupuncture is significantly better than that of traditional acupuncture therapy.It can significantly improve the limb motor dysfunction after acute stroke and improve the daily life ability of patients.3.The needling deqi sensation produced by transcranial repetitive acupuncture stimulation therapy has a potential association with the rehabilitation of limb motor dysfunction in acute ischemic stroke. |
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