Analysis Of Risk Factors Of Urosepsis Before Ureteral Stent Implantation In Patients With Renal Colic During Pregnancy

Background Sepsis is a life-threatening organ dysfunction syndrome caused by dysregulation of host response to infection,which affects millions of people every year,generally showing high fatality rate,poor prognosis and heavy economic burden,and has attracted great attention and attention from countries around the world.Maternal sepsis is the third leading direct cause of maternal death worldwide.The infection source of urinary-derived sepsis comes from the urogenital tract,and urinary-derived sepsis during pregnancy generally presents the characteristics of inobvious early symptoms,rapid disease progression and poor prognosis.If the disease is missed in the early stage and delayed in the treatment opportunity,it is easy to rapidly progress into septic shock,endangering the life of the mother and fetus.Therefore,urinary sepsis during pregnancy should be paid more attention to by urologists.Urine pregnancy merge source sex sepsis has its particularity,the reported cases before surgical intervention,the basic has been urine source sex sepsis or progress for septic shock,suggests we should attach great importance to the repeated renal colic during pregnancy and conservative treatment is invalid,actively looking for sensitive early warning indicators,early recognition of urine source sex sepsis patients with high-risk pregnancy,Surgical interventions such as ureteral stent implantation or renal puncture and stomy can reduce the incidence of urinary-derived sepsis,so as to save the life of fetus and mother.In this paper,the risk factors of ureterogenic sepsis before ureteral stent implantation in patients with renal colic during pregnancy were analyzed to provide a basis for further research on the risk factors related to this disease.MethodsWe retrospectively analyzed the medical records of patients admitted to our hospital for treatment of renal colic during pregnancy from February 1,2016 to February 1,2021.All cases were diagnosed on the basis of clinical manifestations,and renal colic was confirmed by urine analysis and urinary system color ultrasound,and a patient database was established.Patients with urinogenic sepsis prior to ureteral stent implantation were assigned to the experimental group,and patients without urinogenic sepsis were assigned to the control group.SPSS21.0 statistical software was used to analyze the clinical data of the patients.Binary multivariate logistic regression analysis was used to evaluate the independent risk factors of urinary-derived sepsis in patients with renal colic during pregnancy before ureteral stent implantation.ResultsUnivariate analysis showed that gestational age,procalcitonin,positive urine culture,history of urinary calculi and grade of hydronephrosis were related risk factors of ureteral sepsis before ureteral stent implantation in patients with renal colic during pregnancy.The results of multivariate logistic regression analysis showed that older gestational age,procalcitonin ≥ 1.5μg/L,positive urine culture,history of urinary calculi and grade 2 of hydronephrosis were independent risk factors for ureteral sepsis before ureteral stent implantation in patients with renal colic during pregnancy.The results showed that older gestational age(p=0.042),procalcitonin ≥ 1.5μg/L(p=0.013),positive urine culture(p=0.038),history of urolithiasis(p=0.027)and hydronephrosis grade>2(p=0.001)were independent risk factors for ureteral sepsis before ureteral stent implantation in patients with renal colic during pregnancy.ConclusionsOlder gestational age,procalcitonin ≥ 1.5μg/L,positive urine culture before operation,history of urinary calculi and grade 2 of hydronephrosis were independent risk factors for ureteral sepsis before ureteral stent implantation in patients with renal colic during pregnancy.For patients with renal colic during pregnancy,if the above risk factors are found by early screening,after conservative treatment is ineffective,measures such as early empirical antibiotic treatment and active placement of ureteral stents can be taken to control the source of infection,which can reduce the occurrence of urogenic sepsis,so as to reduce the occurrence of maternal and fetal adverse outcomes.