| Objective:To investigate the relationship between abnormal strains and premature rupture of membranes(PROM)in the third trimester of pregnancy.Methods:A total of206 women giving birth in our hospital were randomly selected.There were 103 cases of broken water in the observation group(group A).A total of 103 cases of normal pregnancy in the same period were included in the control group(group B).The prenatal vaginal secretions of the two groups were collected,and the abnormal reproductive tract infections such as group B streptococcus and ureaplasma urealyticum between the two groups were compared,and drug sensitivity analysis was conducted.At the same time,according to different groups,neonatal asphyxia,chorionic amnionitis and other adverse pregnancy outcomes were compared one by one.The correlation between the duration of rupture and adverse pregnancy outcomes was further investigated.Results:The infection rate of genital tract in the observation group was higher than that in the control group(P < 0.001),and the detection rates of chlamydia trachomatis and mycoplasma urealyticum were increased(P < 0.05).Comparison of pregnancy outcome and neonatal birth weight showed statistically significant differences.The longer the duration of water breaking,the greater the correlation between premature delivery,amnionitis and neonatal asphyxia,and the higher the detection rate of bacteria(P=0.025).There was no significant correlation with maternal age,primipara and delivery mode.Drug sensitivity analysis: quinolones drugs have obvious resistance or tend to be resistant.Conclusion: Premature rupture of membranes is closely related to lower genital tract infection.Quinolones are resistant or tend to be resistant to lower genital tract infections.The longer the duration of PROM,the higher the incidence of adverse pregnancy outcomes.In the premature rupture of membranes group,the infection rate of abnormal strains was relatively high. |