Correlation Between Triglyceride-glucose Index And Spontaneous Recanalization Of Infarct-related Artery In Patients With Acute Myocardial Infarction

Objective:This study intends to investigate the relationship between the triglyceride-glucose index and spontaneous recanalization of infarct-related artery blood flow in patients with acute ST-segment elevation myocardial infarction.Methods: A total of 227 patients with acute STEMI were selected from January2018 to December 2018 and underwent coronary angiography.According to the results,they were divided into spontaneous recanalization group（65 cases）and non-spontaneous recanalization group（162 cases）.Collection of two groups of patients’ age,gender,smoking,drinking,hypertension,body mass index,lesion blood vessel counts,the infarction related blood vessels,systolic blood pressure,heart rate,left ventricular ejection fraction,left ventricular end-diastolic diameter,white blood cell count,hemoglobin level,fasting plasma glucose levels,serum creatinine levels,high density lipoprotein cholesterol,low-density lipoprotein cholesterol levels,total cholesterol level,triglyceride level,apolipoprotein A1 level,apolipoprotein B level,etc.The results of coronary angiography were recorded,and Ty G index and Gensini score were calculated.The collected data were analyzed with IBM SPSS26.0 software,and P < 0.05 was considered statistically significant.Results: 1.There were 227 STEMI patients who met the inclusion criteria,65 patients with spontaneous recanalization in the infarct-related artery,and 162 patients with non-spontaneous in the infarct-related artery.The spontaneous recanalization rate was 28.6%.2.Comparison of data between the two groups2.1 SR group（65 persons）: aged between 40 and 83 years,with an average age of62.7±10.2 years;There were 36 males（55.4%）and 29 females（44.6%）.38 smokers（58.5%）;18 people（27.7%）drank alcohol;36 patients（55.4%）had hypertension.2.2 NSR group（162 persons）: aged between 39 and 82 years,with an average age of60.9±9.2 years;There were 97 males（59.9%）and 65 females（40.1%）;83 smokers（51.2%）;52 people（32.1%）drank alcohol;68 patients（51%）had hypertension.2.3 Compare the data of the two groups of patients with spontaneous recanalization:The white blood cell count,fasting plasma glucose,Gensini score,Ty G index of the two group was statistically significant（P<0.05）,there were no significant differens in other indicators between the two groups（P>0.05）.Taking statistically significant factors（P<0.05）as independent variables and spontaneous recanalization as dependent variables,Logistic multifactor regression analysis showed that the triglyceride-glucose index（OR=3.145,95%CI=1.941-5.096,P<0.05）and white blood cell count（OR=1.164,95%CI=1.047-1.295,P< 0.05）were the influencing factors of spontaneous recanalization of infarct-related artery in patients with acute ST-segment elevation myocardial infarction.3.Spearman correlation analysis was performed on the triglyceride-glucose index and Gensini score.The results showed that the triglyceride-glucose index was positively correlated with Gensini score（rs = 0.226,P = 0.001）.Conclusion :1.The spontaneous recanalization rate of infarct-related arteries in STEMI patients was 28.6%;2.White blood cell count and triglyceride-glucose index are independent influencing factors of spontaneous recanalization of infarct-related artery in STEMI patients;3.Triglyceride-glucose index was positively correlated with coronary Gensini score.