Professor Ni Cheng's Theoretical Inheritance And Data Mining Research On The Treatment Of Metabolic Syndrome By Distinguishing Body And Disease

Objective:Through theoretical analysis and data mining comparative analysis of the ideas and prescriptions of the clinical treatment of metabolic syndrome by Professor Ni Cheng and Academician Wang Qi,we will explore and verify the inheritance and reproducibility of well-known TCM thoughts and experiences.Improve the clinical diagnosis and treatment of metabolic syndrome to provide new ideas and methods.Methods:1 Research on the Theoretical Inheritance of Academician Wang Qi and Professor Ni Cheng by Differentiating Body and Disease Treatment of Metabolic SyndromeThrough online and offline access to relevant literature,listening to a series of courses and lectures,regular outpatient clinics to learn from teachers and review related outpatient materials,etc.,to summarize the main academic thoughts and experiences of Academician Wang Qi and Professor Ni Cheng in the diagnosis and treatment of metabolic syndrome.And analyze the inheritance characteristics of Professor Ni Cheng to Academician Wang Qi's treatment of metabolic syndrome.2 Research on Data Mining of Academician Wang Qi and Professor Ni Cheng in Differentiating Body and Disease Treatment of Metabolic SyndromeThis topic collected medical records from Academician Wang Qi's outpatient clinic for metabolic syndrome from July 2016 to December 2020,and finally included a total of 138 medical records with a total of 200 visits;collected from July 2014 to December 2020 During the period,the medical records of the professor's outpatient treatment of metabolic syndrome included 176 medical records and a total of 331 visits.After standardized processing of the diseases,prescriptions and other materials in the medical records of Academician Wang Qi and Professor Ni Cheng,they were entered into the traditional Chinese medicine inheritance auxiliary platform to establish their own databases,and data mining methods such as frequency analysis,association rules,and complex system entropy clustering were used.A comparative analysis of the prescription medication rules between Academician Wang Qi and Professor Ni Cheng for the treatment of metabolic syndrome,and further explore the academic inheritance of Professor Ni Cheng's diagnosis and treatment of metabolic syndrome.Results:1 Research on the Theoretical Inheritance of Academician Wang Qi and Professor Ni Cheng by Differentiating Body and Disease Treatment of Metabolic SyndromeIn terms of pathogenesis,Professor Ni Cheng inherited the pathogenesis of metabolic syndrome related to physical fitness proposed by Academician Wang Qi.In terms of pathogenesis,Professor Ni Cheng inherited academician Wang Qi's understanding of the pathogenesis of metabolic syndrome and believed that phlegm-damp constitution is the main"common soil" for metabolic diseases,which can appear alone and often contain other physiques.Types of disease,phlegm dampness and blood stasis,and loss of transportation and transformation are the main pathogenesis of metabolic syndrome.In terms of therapeutics,Professor Ni Cheng inherited the diagnosis and treatment model that combines body differentiation and disease differentiation proposed by Academician Wang Qi,that is,adding or subtracting medication for specific physique and disease conditions on the basis of regulating phlegm and damp constitution.In regulating the physique of phlegm and dampness,Academician Wang Qi formulated the "Yiqi Jianyun Decoction" with the legislation of invigorating qi and strengthening the spleen,warming the kidney and assisting yang,resolving phlegm and dampness,eliminating food and blood stasis,and Professor Ni Cheng on it In the analysis of the formulation of the formula,we further summarized the medication ideas of "three pyrolysis" and "aromatization of dampness".In the treatment of obesity,most of the drugs used by Professor Wang Qi to treat obesity are drugs for regulating phlegm and dampness.Professor Ni Cheng further put forward the "bitterness and sweetness" medication concept based on the experience of Academician Wang Qi and attaches importance to the application of TCM abdominal diagnosis.In the treatment of fatty liver,Professor Ni Cheng based on Professor Wang Qi's treatment of promoting blood circulation,removing phlegm and eliminating fat,especially for patients with moderate to severe fatty liver.On the basis of Qi-yin double-toning,soreness and bitterness to relieve heat,and phlegm-removing congestion treatment method,academician Qi also used the method of aromatizing turbidity,promoting blood circulation and removing blood stasis;in the treatment of hypertension,Professor Ni Cheng inherited academician Wang Qi's Qinggan Zhenni The method of promoting blood circulation and diuresis,and attaches importance to the application of the method of promoting blood circulation and diuresis;when treating hyperuricemia,Professor Ni Cheng used the method of warming the kidney and promoting yang on the basis of the method of turbidity and detoxification by academician Wang Qi2 Research on Data Mining of Academician Wang Qi and Professor Ni Cheng in Differentiating Body and Disease Treatment of Metabolic SyndromeThrough the analysis of the physique types of 314 patients in the outpatient clinic of Academician Wang Qi and Professor Ni Cheng,91 cases were found to have phlegm-damp constitution,70 cases of phlegm-dampness and blood stasis,56 cases of phlegm-dampness and damp-heat constitution,and phlegm-dampness,damp-heat and blood stasis.23 cases of physique,20 cases of phlegm-dampness,deficiency of qi with blood stasis,etc.;statistics of patients suffering from diseases showed that there were 308 cases of central obesity,274 cases of dyslipidemia,232 cases of fatty liver,146 cases of hyperglycemia,and 119 cases of hypertension.Cases,61 cases of hyperuricemia,etc.According to the research of academician Wang Qi and Professor Ni Cheng,the commonly used drugs for regulating phlegm and damp constitution are tangerine peel,cinnamon,fried atractylodes,lotus leaf,turmeric,Alisma orientalis,raw hawthorn,raw astragalus,kelp,Poria,Seaweed,Raw Typhae,Fried Scutellaria;Ni Cheng Professor's commonly used drugs for regulating phlegm and dampness are tangerine peel,cinnamon,fried atractylodes,lotus leaf,turmeric,Alisma,raw hawthorn,raw astragalus,kelp,poria,seaweed,Raw puhuang,fried raisin,calamus and cassia sticks.Academician Wang Qi uses Yinchen and Coptis for conditioning and damp-heat constitution,and Yinchen is the main medicine.Ni Cheng Professor,those who regulate and damp-heat constitution often use Coptis and Scutellaria.Academician Wang Qi uses raw typhae,turmeric,peach kernels,and safflower to treat people with blood stasis,and mainly raw typhae and turmeric.Ni Cheng Professor often uses peach kernels and safflower,raw typhae and turmeric medicine Regulate those who have a physique with blood stasis.Academician Wang Qi and Professor Ni Cheng both often increase the amount of raw astragalus,and add atractylodes macrocephala to regulate people with qi deficiencyResearch on the prescription drugs used by Academician Wang Qi and Professor Ni Cheng for the treatment of central obesity found that the drugs commonly used by Academician Wang Qi for the treatment of central obesity are tangerine peel,cinnamon,fried atractylodes,lotus leaf,raw hawthorn,raw astragalus,tuckahoe,raw Puhuang,fried raspberry seeds,turmeric,Alisma,kelp,seaweed,etc.and divine comedy,red yeast rice;Professor Ni Cheng often uses tangerine peel,cinnamon,fried atractylodes,lotus leaf,raw hawthorn,raw astragalus,poria,raw puhuang,Fried raisin,turmeric,Alisma orientalis,kelp,seaweed,etc with calamus,cassia twig,coptis,magnolia officinalis,citrus aurantium,rigid silkworm.The association rule analysis of academician Wang Qi's prescription for the treatment of central obesity has set a support degree of 46 and a confidence level of 0.8.It can be seen that tangerine peel-cinnamon,tangerine peel-lotus leaf,tangerine peel-fried atractylodes,cinnamon-lotus leaf,tangerine peel-cinnamon-lotus leaf,Cinnamon-fried atractylodes,tangerine peel-cinnamon-fried atractylodes,lotus leaf-fried atractylodes,tangerine peel-lotus leaf-fried atractylodes combs appear more frequently;Poria->Alisma orientalis,cinnamon,raw hawthorn->tangerine peel,lotus leaf,raw hawthorn->Tangerine peel,cinnamon,lotus leaf->Tangerine peel,cinnamon,raw astragalus->Tangerine peel,cinnamon,lotus leaf,stir-fried atractylodes,and other combinations have a higher correlation degree;through entropy clustering method,set the correlation degree to 8 and punish With a degree of 2,the analysis can find drug combinations such as cinnamon-raw rhubarb,kelp-dried tangerine peel,kelp-wax gourd peel,kelp-raw puhuang,red yeast rice-turmeric,turmeric-Gallus gallus domesticus,etc.The core drug combination includes kelp_Raw hawthorn_Seaweed,Alisma orientalis_winter melon skin_seaweed,fried raisin_red yeast_amom,raw puhuang_turmeric_raw hawthorn,etc.Analyzed the association rules of Professor Ni Cheng's prescription for the treatment of central obesity,set the support degree of 126,and the confidence level of 0.8.It was found that raw hawthorn-fried scutellaria,coptis-raw hawthorn,coptis-fried scutellaria,coptis-raw hawthorn-fried scutellaria Coptis,Poria,Raw Hawthorn->Fried Scutellaria,Magnolia officinalis->Fried Scutellaria,Coptis,Poria->Fried Scutellaria,Coptis,Fried Scutellaria->Raw Hawthorn and other combinations are more relevant High;through the entropy clustering method,setting the correlation degree to 10 and the penalty degree to 5,the analysis can find the drug combinations such as tangerine peel-citrus aurantium,tangerine peel-pumice stone,tangerine peel-seaweed,tangerine peel-kelp,magnolia-rhubarb,etc.;drugs The core combination is tangerine peel,fried atractylodes,Alisma orientalis,seaweed,raw puhuang,turmeric,lotus leaf,magnolia,cohosh,cohosh,cooked rhubarb,kelp,cinnamon,fried atractylodes,cooked rhubarb,citrus aurantium,calamus,etc.In the analysis of the drugs used by Academician Wang Qi and Professor Ni Cheng for the treatment of dyslipidemia and fatty liver respectively,it was found that Academician Wang Qi used raw hawthorn,lotus leaf,seaweed,kelp,turmeric,raw cattail yellow,and fried cassia seeds when treating dyslipidemia and fatty liver.,Gynostemma pentaphyllum,and cooked rhubarb;Professor Ni Cheng often uses raw hawthorn,raw puhuang,cooked rhubarb,roasted turtle worms,etc.in the treatment of fatty liver.For moderate to severe fatty liver,rhubarb or rhubarb capsules are used.In the analysis of the drugs used in the clinical treatment of hyperglycemia by Academician Wang Qi and Professor Ni Cheng,it was found that the drugs commonly used by Academician Wang Qi in the diagnosis and treatment of hyperglycemia were Coptis,raw astragalus,mulberry,ebony,pueraria lobata,rhizome,raw rehmannia,scorpion silkworm,etc.Arrow feathers,Gallus gallus domesticus,almonds,and the drugs that Professor Ni Cheng often use for diagnosis and treatment of hyperglycemia are Coptis,raw astragalus,mulberry,ebony,kudzu root,polygonatum,rehmannia glutinosa,silkworm,etc.,as well as Peilan and safflower.In the analysis of academician Wang Qi and Professor Ni Cheng's clinical treatment of hypertension,it was found that Academician Wang Qi often used Pueraria lobata,Achyranthes bidentata,Sophora japonica,Zhuru,Poria,Alisma,etc.,and Professor Ni Cheng most often diagnoses and treats hypertension The medicine used is Sichuan Achyranthes bidentata.In the analysis of the drugs used by Academician Wang Qi and Professor Ni Cheng in the clinical treatment of hyperuricemia,it was found that Academician Wang Qi often used yam rhizome,Smilax chinensis,etc.and turmeric;Professor Ni Cheng's commonly used drugs for the diagnosis and treatment of hyperuricemia were Poria cocos,Smilax chinensis Wait with Plantago and Qinpi.Seeing that when gout attacks,Professor Wang Qi added honeysuckle,Scrophulariaceae,Angelica,licorice,Dia eargrass,Poisonous grass,Wei Lingxian,etc.;Professor Ni Cheng added Paofuzi,Guizhi,Stir-fried Atractylodes,raw licorice,Zhimu,Wei Lingxian and so on.Conclusion:1 By analyzing and summarizing the characteristics of Professor Ni Cheng's theoretical inheritance of academician Wang Qi's treatment of metabolic syndrome,it shows that the thoughts and experiences of famous Chinese medicine can be inherited and reproducible.2 Through further comparative analysis and research on the prescription medication rules of academician Wang Qi and Professor Ni Cheng for the treatment of metabolic syndrome,it is found that Professor Ni Cheng inherited the ideas and experience of academician Wang Qi's body differentiation and disease treatment of metabolic syndrome,New explorations have been made in the prescription and medication,which will help to further improve the clinical diagnosis and treatment efficacy of metabolic syndrome.