Preparation And Application Of Ointment For Controlling Seabuckthorn Dry Rot

Pesticide paste is a flowable dispersion system made by wet grinding of raw materials,wetting dispersants,thickeners,stabilizers,and other additives.The paste has many advantages of emulsion and wettable powder,such as using little or no organic solvents compared to emulsion,and having better suspension performance compared to wettable powder.Diaporthe spp.and Diaporthe eres can cause a variety of woody plant disease,such as branch blight,shoot blight,etc.,which can cause plant death in serious cases.Many woody plants have been infected with dry rot caused by this fungus.This article focuses on the prevention and control of fungi in the genera Interstitial Shell and Black Rotted Shell.Tebuconazole is used as the raw material,and a new type of viscous paste or gel suspension agent is developed by adding wetting dispersants,thickeners,and other additives.It is applied to the diseased parts of trees to achieve disease prevention effects.The development and application process of rubber suspension agent includes the following contents.1 、 Indoor toxicity test to determine the best crude drug: in this experiment,the toxicity of the 10 fungicides to the fungi of the genus Mesenchyma is in the following order: 25% prochloraz emulsifiable concentrate>430g/L tebuconazole suspension>250g/L azoxystrobin suspension>25% pyrazofon suspension>75% chlorothalonil wettable powder>50% carbendazim wettable powder>70% thiophanate methyl wettable powder>15% triadimefon wettable powder>70% propionyl wettable powder>80%mancozeb Wettable powder;The order of toxicity to the fungi of the genus Phanerochaete is: 250g/L azoxystrobin suspension>25% prochloraz emulsifiable concentrates>430g/L tebuconazole suspension>50% carbendazim wettable powders>25% pyrazolidin suspension>75% chlorothalonil wettable powders>15% triadimefon wettable powders>70% prochloraz wettable powders>70% thiophanate wettable powders>80%mancozeb wettable powders.The indoor toxicity test results show that 25% prochloraz emulsifiable concentrates 430g/L Tebuconazole suspension agent and 250g/L Azoxystrobin suspension agent have good inhibitory effects on the fungi of the genus Mesenchyma and the genus Black Rot.2.Field trials to determine the optimal raw material: In 2022,field trials were conducted in Ejin Horo Banner,with a total of 9 different treatments.Finally,430g/L tebuconazole suspension was determined as the optimal fungicide and achieved good control effects.The field efficacy is as follows: 430g/L tebuconazole suspension>50%carbendazim wettable powder>80% mancozeb wettable powder>25% pyrazolidin suspension>70% thiophanate methyl wettable powder>15% triadimefon wettable powder>250g/L azoxystrobin suspension>70% propionium wettable powder>75%chlorothalonil wettable powder.The field test results show that 430g/L tebuconazole suspension has the best control effect on dry rot.3.Development and quality evaluation of dosage forms: By screening different wetting dispersants,thickeners,etc.,the formula of 1% tebuconazole ointment was screened.Finally,the formula of tebuconazole paste was determined as follows:tebuconazole technical drug 1%,wetting dispersant DL-RF 0.1%,thickening agent Xanthan gum 3%,and deionized water supplemented to 100%.Based on the physical and chemical properties of the paste and in order to ensure the stability of 1% tebuconazole paste,a quality inspection standard has been established.The content of active ingredients is detected using high-performance liquid chromatography,and its viscosity,suspension rate,and other indicators are tested.4.The Field Control Effect of Tebuconazole Ointment on Seabuckthorn Dry Rot Disease: In 2023,a field trial was conducted in Ejin Horo Banner,setting up three different treatments.The order of field efficacy was: Shijia Garden Ointment>Tebuconazole Ointment>Water Application.The test results showed that the Tebuconazole Ointment developed in this experiment had similar control effects to Shijia Garden Ointment,with38.94% and 32.01%,respectively,showing good control effects on Seabuckthorn Dry Rot Disease,And no drug harm or other adverse reactions were found in the experiment.