Predictive Value Of MRI Infarct Volume And Biochemical Indexes In Hemorrhagic Transformation Of Cardiac Stroke

Objective:To investigate the relationship between hemorrhagic transformation after anticoagulation therapy in patients with cardiogenic stroke and the MRI infarct volume and related biochemical indicators before treatment.Method:To collect 306 patients who underwent anticoagulation therapy for cardiogenic stroke in our hospital from March 2017 to March 2020.Among them,69 received rivaroxaban,57 received dabigatran,and 120 received Warfarin treatment.All patients underwent cranial MRI and related biochemical index examinations on admission.Calculate the volume of the patient’s cerebral infarction,evaluate the patient’s NIHSS score and mRs score,re-evaluate the NIHSS score on the 7th and 14th day of enrollment,and recheck the magnetic resonance susceptibility imaging on the 14th and 30th day of enrollment to determine whether there is hemorrhagic transformation.Results:The incidence of hemorrhagic transformation in the rivaroxaban group was 21.7%,the incidence in the dabiga group was 31.6%,the incidence in the warfarin group was 25.6%,and the incidence of the aspirin group was 0%,the difference between the anticoagulation treatment group and the non-anticoagulation treatment group was statistically significant(P<0.05),There was no significant difference between the three anticoagulation treatment groups(P>0.05);Smoking history,D-Ⅱpolymer,PT,fasting blood glucose,and MRI infarct volume are all risk factors for hemorrhagic transformation of acute cerebral infarction;D-Ⅱ polymer,fasting blood glucose,and MRI infarct volume have diagnostic effects on hemorrhagic transformation of cardiogenic stroke with anticoagulants(P<0.05).Conclusion:D-Ⅱ polymer,fasting blood glucose and MRI infarct volume have predictive value for hemorrhagic transformation after anticoagulant therapy in cardiogenic stroke.