Clinical Observation Of Yinmei Decoction In The Treatment Of Insomnia Patients With Liver Blood Deficiency

Objective : To observe the clinical efficacy of Yinmei Decoction in the treatment of liver-blood deficiency insomnia.In order to provide new ideas for the diagnosis and treatment of insomnia with traditional Chinese medicine.Methods: Seventy patients with insomnia of liver-blood deficiency type who met the inclusion criteria were randomly divided into two groups by random number table method.The treatment group,35 cases,was treated with Yinmei Decoction and zopiclone;the control group,35 cases,was treated with zopiclone.After 4 weeks of treatment,the scores of PSQI,FS-14 and TCM Syndrome Scale were observed in the two groups before and after treatment.Analysis and evaluation of the clinical efficacy of intervention.Results: During the treatment,2 cases in the treatment group dropped out,and 33 cases in the final treatment group were completed;4cases in the control group dropped out,and 31 cases in the control group were completed in the end.(1)Comparison of PSQI score: the total PSQI score and individual PSQI score of the two groups after treatment were significantly lower than those before treatment(P<0.05);after treatment,the total and individual PSQI scores in the treatment group were significantly lower than those in the control group(P <0.05).(2)Comparison of FS-14 scores : FS-14 scores in both groups after treatment were significantly lower than those before treatment(P<0.05);after treatment,the FS-14 score in the treatment group was significantly lower than that in the control group(P < 0.05).(3)Comparison of TCM syndromes: the total score and single score of TCM syndromes in the two groups after treatment were significantly lower than those before treatment(P<0.05);after treatment,the total scores of TCM syndromes and eight individual scores,including difficulty to fall asleep,easy to wake up/shallow to sleep/early to wake up,insomnia all night,poor daytime mental state,pale or yellowish face,dizziness,dry eyes and blurred vision,in the treatment group were significantly lower than those in the control group(P < 0.05).There was no significant difference in single score of hand foot numbness between groups(P>0.05).(4)Comparison of curative effect: The effective rate of sleep quality(93.9%)and the effective rate of TCM syndromes(90.9%)in the treatment group were better than those in the control group(P<0.05).Conclusion: The therapeutic effect of Yinmei Decoction combined with zopiclone in the treatment of insomnia is remarkable.It is better than zopiclone alone in improving sleep quality,relieving symptoms of liver blood deficiency and fatigue,and improving daytime function.Yinmei Decoction is safe in clinical application,has no adverse reactions,and is worthy of promotion.