| Objective:Observe the curative effect and effects on the serum MMP-9 content of Buzhong Yiqi Decoction combined with pelvic floor rehabilitation in treating POP patients with pi-qi-deficiency syndrome.Compared with using pelvic floor rehabilitation alone.To explore the efficacy of Buzhong Yiqi Decoction combined with pelvic floor rehabilitation for POP.The relationship between serum MMP-9 content and POP is discussed.Enrich the theoretical basis of integrated traditional Chinese and western medicine in the treatment of POP.Methods:A total of 70 patients with POP who met the inclusion criteria were divided into treatment and control groups,with 35 patients in each group.The control group was treated with pelvic floor rehabilitation,and the treatment group was added with Buzhong Yiqi Decoction based on the control group for a total of 3 months.POP-Q scores,PFDI-20 score,TCM syndrome score,pelvic floor surface EMG assessment values,and serum MMP-9content were collected before and after treatment,and the data were statistically analyzed to assess efficacy.Results:1.curative effectClinical efficacy: The response rate was 76.47% in the control group and 88.23%in the treatment group,and significantly improved in the treatment group(P <0.05);Efficacy of TCM syndrome:Effective rate was 76.47% in control group,91.18% in tre atment group,and significantly improved(P <0.05);It showed that both treatments hadgood efficacy and the treatment group was better than the control group.2.Clinical symptoms improvedThe PFDI-20 score and TCM syndrome score were improved after treatment in both groups.Statistically significant difference compared to before treatment(P <0.05);PFDI-20 score and TCM syndrome score improved significantly compared with control group(P<0.05);It shows that both treatments can improve the PFDI-20 score and the TCM syndrome score.The effect was better in the treatment group.3.Pelvic floor muscle functionThe test values increased at all stages of pelvic floor EMG assessment in both groups compared with pre-treatment(P <0.05);The test values of pelvic floor EMG assessment were significantly improved in the treatment group compared with the control group(P <0.05);This indicates that both treatments could improve pelvic floor muscle function,and the improvement in the treatment group was better than in the control group.4.Serum MMP-9 contentThere was a positive rank correlation between serum MMP-9 content and POP-Q score before treatment(P <0.05).Serum MMP-9 decreased after treatment compared with before treatment(P <0.05);Serum MMP-9 content in the treated group was significantly lower than that in the control group(P <0.05).This indicated that both treatments could reduce the serum MMP-9 content with better results in the treatment group.Conclusion:1.The simple use of pelvic floor rehabilitation and Buzhong Yiqi Decoction combined with POP patients have good effect,which can improve the TCM syndrome score,PFDI-20 score and pelvic floor surface EMG evaluation value,and the combined effect is more obvious.2.Serum content of MMP-9 may be related to the severity of POP.Simple use of pelvic floor rehabilitation and Buzhong Yiqi Decoction combined with pelvic floor rehabilitation can reduce the serum content of MMP-9,and the effect of the two is more obvious. |
