| Objectives:To observe the clinical efficacy and safety of Ginseng Bufei Decoction on stable chronic obstructive pulmonary disease（lung-kidney qi deficiency and stasis syndrome）.Methods:From February 2021 to January 2022,64 patients with stable chronic obstructive pulmonary disease with lung-kidney qi deficiency and blood stasis were selected and randomly divided into treatment group and control group.There were 32 cases in each group,the control group was given conventional western medicine treatment,and the treatment group was given the addition and subtraction of Ginseng Bufei Decoction on the basis of conventional western medicine treatment for 12 weeks.The TCM syndrome scores,clinical efficacy,COPD assessment test（CAT）,pulmonary function（FEV1%pred,FEV1/FVC）,dyspnea index（m MRC）and six-minute walking distance（6MWD）were observed in the two groups before and after treatment.Changes.Results:1.This experiment finally included 61 patients with stable chronic obstructive pulmonary disease（lung-kidney qi deficiency and stasis syndrome）,31 patients in the treatment group and 30 in the control group.There was no significant difference between the two groups in gender,age,course of disease,COPD comprehensive assessment grouping,GOLD classification and other baselines（P>0.05）,and the two groups were comparable.2.After treatment,the total effective rate was 93.55%in the treatment group and 73.33%in the control group,the difference was significant（P<0.05）.3.After treatment,the total scores of TCM symptoms in both groups were improved,and the improvement in the treatment group was better than that in the control group（P<0.05）.After treatment,all TCM symptom scores in the treatment group were improved（P<0.05）,while in the control group,only cough,expectoration,wheezing,shortness of breath,fatigue,spontaneous perspiration,aversion to wind,and soreness of the waist and knee were improved（P<0.05）.However,there was no significant improvement in susceptibility,frequency of urination,dark complexion,and blue lips（P>0.05）.The treatment group and the control group had similar effects in improving cough,expectoration,wheezing,shortness of breath,and fatigue（P>0.05）.The treatment group was better in improving spontaneous perspiration and aversion to wind,soreness and weakness of waist and knees,susceptibility,frequent urination,dark complexion,and blue lips（P<0.05）.4.There was no significant improvement in pulmonary function（FEV1%pred,FEV1/FVC）in both groups after treatment（P>0.05）.After treatment,CAT,m MRC and 6MWD in the two groups were improved compared with those before treatment（P<0.05）,and the improvement degree of CAT,m MRC and 6MWD in the treatment group was better than that in the control group（P<0.05）.5.There were no adverse reactions in both groups during the treatment period.Conclusions:1.The total effective rate of Ginseng Bufei Decoction combined with conventional western medicine in the treatment of patients with stable chronic obstructive pulmonary disease（lung-kidney qi deficiency and stasis syndrome）is better than that of conventional western medicine alone,which can significantly relieve clinical symptoms and improve the quality of life of patients.2.Ginseng Bufei Decoction combined with conventional western medicine in the treatment of patients with stable chronic obstructive pulmonary disease（lung-kidney qi deficiency and stasis syndrome）can improve exercise endurance and reduce dyspnea.3.Ginseng Bufei Decoction combined with conventional western medicine is safe and effective,and is worthy of further promotion. |
