Design And Evaluation Of Rehabilitation Training Paradigm For Hand Dysfunction Based On Virtual Reality

Stroke patients commonly develop limb motor dysfunction,and 50% to 70% of the survivors still have hand dysfunction 2 to 4 years after stroke.How to more effectively help stroke patients restore hand function is an important content that researchers have been paying attention to.Rehabilitation exercise training based on virtual reality(VR)can help to improve patients’ active participation,and it is an important means of rehabilitation of hand dysfunction.Based on the VR rehabilitation game developed for hand dysfunction rehabilitation training,starting from the design of the VR-based hand dysfunction rehabilitation training paradigm,combined with the functional near-infrared spectroscopy technology,the impact of the rehabilitation exercise paradigm on the brain function of stroke patients is quantitatively evaluated,so as to explore an effective hand dysfunction rehabilitation training paradigm and provide a reference for clinical rehabilitation training plans.First,the design method of VR-based rehabilitation training paradigm for hand dysfunction is elaborated.The process of design of the entire rehabilitation training paradigm is proposed,including the evaluation of hand function,the selection of rehabilitation training mode,and the selection method of rehabilitation training cycle,frequency and total duration.And put forward the VR-based hand dysfunction rehabilitation training paradigm design needs to follow the design principles.Second,a VR rehabilitation game was designed based on Unity3 D and sensing devices.VR rehabilitation game design includes two parts: game scene construction and script design.First,the game scene construction: according to the needs of the rehabilitation training paradigm,the VR rehabilitation game scene needs to make personalized adjustments to the frequency of movement,exercise time and activity angle,so the scene of the road program is selected.The second is script design: the script function mainly includes game character control and sensor signal reading and writing,reading the sensor signal through the script,and establishing the mapping relationship between the variables and the sensor measurements in the script,so as to realize the patient control of the game character and the acquisition of game data.Third,an assessment method based on the VR rehabilitation training paradigm for hand dysfunction is proposed,that is,an evaluation method that combines brain function detection and exercise parameters correlation analysis.During VR rehabilitation training,patients collect cerebral blood oxygen signals and VR rehabilitation game data.During the evaluation,first of all,through the data processing and analysis of cerebral blood oxygen signals,the activation intensity of brain regions and the strength of brain functional connectivity between brain regions are obtained,so as to evaluate the effect of rehabilitation training paradigm on brain function rehabilitation.Secondly,the data processing of VR rehabilitation game data is carried out,the exercise parameters are calculated,and the correlation between the movement parameters and the activation intensity of the brain area is analyzed,so as to evaluate the influence of the training cycle and frequency set in the rehabilitation training paradigm on the rehabilitation effect.Finally,experiments are designed to verify the effectiveness of a paradigm assessment method for rehabilitation training for hand dysfunction based on VR.Experiments have verified the VR-based grip movement paradigm,which can improve the activation of contralateral brain regions of motor limbs and the strength of brain functional connectivity,while inhibiting brain functional connectivity of the ipsilateral brain regions of motor limbs,reasonably adjusting the allocation of brain resources in patients,and promoting the recovery of hand function.Finally,the effectiveness of the evaluation method is verified.