Cross-cultural Adaptation Of The Manchester COPD Fatigue Scale And The Current Situation Of Fatigue In Patients With Stable Chronic Obstructive Pulmonary Disease

Objective1.The Manchester COPD Fatigue Scale(MCFS)was introduced and translated into Chinese,based on Chinese national conditions and cultural background,establish the Chinese version of MCFS.2.To test the reliability and validity of MCFS scale,and explore its applicability in stable COPD patients in China.3.The MCFS scale was used to conduct a cross-sectional survey of stable COPD patients to understand the current situation of fatigue in stable COPD patients and analyze the fatigue related factors,so as to provide a basis for clinical workers to study the fatigue related intervention in stable COPD patients.Methods1.After obtaining informed consent and authorization for the use of the scale from the author of the source scale via email,from January 2021 to February 2021,the Manchester COPD Fatigue Scale(MCFS)was translated,back translated,and cross-cultural adapted following the Brislin translation model.In February 2021,convenience sampling method was adopted to select 30 stable COPD patients at a tertiary hospital in this city for a preliminary test to evaluate the feasibility of the scale,and finally form a Chinese version of the Manchester COPD Fatigue Scale(MCFS)in line with Chinese national conditions and cultural background.2.The convenience sampling method was used to select 162 stable COPD patients at a tertiary hospital in this city.The patients were investigated using the general condition questionnaire,MCFS and MFI-20.SPSS25.0 software was used for statistical analysis of the collected data.Internal consistency reliability,retest reliability,criterion correlation validity,content validity and structure validity were used to evaluate the reliability and validity of the MCFS.3.The convenience sampling method was used to select 162 stable COPD patients at a tertiary hospital in Hohhot.The patients were investigated using the general condition questionnaire,MCFS,HADS and CAT.SPSS25.0 software was used for statistical analysis of the collected data.In univariate analysis,independent sample t test or ANOVA was used for measurement data subject to normal distribution,and Mann-Whitney U test or Kruskal-Wallis test was used for variables not subject to normal distribution.Multivariate linear regression analysis was conducted for variables with statistical significance in univariate analysis.To determine the major factors affecting fatigue in stable COPD patients.Results1.The Chinese version of MCFS scale included 27 items and 3 dimensions(physical fatigue,cognitive fatigue and psychological fatigue).The cumulative variance contribution rate was 75.159%.The S-CVI of this scale was 0.96,and the I-CVI range was 0.83-1.The MCFS was positively correlated with the total score of MFI-20 scale(r=0.904,P<0.001).The retest reliability of the total score of the scale was r=0.972,and the physical,cognitive,psychological dimensions′s were r=0.985,r=0.981,r=0.991.Cronbach’s α coefficient of MCFS was 0.855 and Cronbach’s α coefficient of physical,cognitive,psychological dimensions were 0.974,0.968 and 0.958.2.The total mean score of MCFS was(24.651±5.094),physical fatigue(9.228±2.649),cognitive fatigue(10.494±2.313),psychological fatigue(4.929±1.488),the overall level of moderate fatigue.Multiple linear regression analysis showed that quality of life level,blood oxygen saturation index,age,anxiety and depression symptom severity were the influencing factors of fatigue in stable COPD patients.Conclusion1.The Chinese version of MCFS has good reliability and validity,and can be used as a specific scale for evaluating fatigue symptoms in stable COPD patients in China.2.In stable COPD patients,the overall level of fatigue was moderate.Quality of life,blood oxygen saturation index,age,anxiety and depression symptom severity were independent influencing factors of fatigue symptoms.3.In the future,clinical workers should improve the understanding of fatigue symptoms in stable COPD patients,formulate systematic and reasonable intervention measures through comprehensive evaluation of factors causing fatigue,effectively reduce the incidence of fatigue in patients and relieve the severity of fatigue,and improve the overall quality of life of patients.