Clinical Observation Of Qiangpo Zhumian Decoction In The Treatment Of Insomnia Disorder With Anxiety

Objective:To observe the clinical effect of Qiangpo Zhumian Decoction in treating insomnia disorder with anxiety,and to deepen the understanding of soul theory,so as to broaden the thinking and provide the basis of syndrome differentiation for clinical treatment of insomnia disorder with anxiety.Methods: A total of 60 patients with insomnia and anxiety were randomly divided into experimental group and control group,30 cases in each group.The experimental group took Qiangpo Zhumian Decoction orally,one dose per day,one bag in the morning and one bag in the evening,half an hour after meals;The control group was treated with conventional western medicine:Alprazolam Tablets was orally taken 30 minutes before sleep.The course of treatment was4 weeks.Hamilton Anxiety Scale(HAMA),Pittsburgh Sleep Index Scale(PSQI)and TCM syndrome score scale were collected before treatment and 2 weeks and4 weeks after treatment,respectively.The clinical efficacy of the two groups was observed and analyzed,and the possible adverse reactions during treatment were closely watched,treated in time and recorded.Results:During the study,1 patient dropped out in the test group and 1patient dropped out in the control group.Finally,a total of 60 patients were included in the statistical analysis.Before treatment,the general information(gender,age),PSQI score,HAMA score,TCM syndrome integral scale score had no statistical difference(P>0.05),the two groups were comparable.From the statistical results,female patients were more than male patients;The age distribution of patients was concentrated between 31 and 60 years.Intra-group comparison: PSQI score,HAMA score and TCM syndrome integral scale score were significantly lower in both groups after 2 weeks and 4 weeks of treatment than before treatment,and after 4 weeks of treatment than after 2 weeks of treatment(P<0.05);Comparison between groups: After 2weeks and 4 weeks of treatment,the PSQI score,HAMA score and TCM syndrome integral scale score of the experimental group were significantly lower than those of the control group,and the differences were statistically significant(P<0.05).After the completion of treatment,the efficacy was evaluated by the PSQI score reduction rate,and the total effective rate of the test group(93.3%)was higher than that of the control group(80.0%);the efficacy was evaluated by the HAMA score reduction rate,and the total effective rate of the test group(96.6%)was higher than that of the control group(80.1%);the efficacy was evaluated by the TCM syndrome score reduction rate,and the total effective rate of the test group(96.7%)was higher than that of the control group(86.7%),and the differences were statistically significant(P<0.05).No obvious adverse reactions were observed during the treatment,and the safety was high.Conclusion:1.Qiangpo Zhumian Decoction and alprazolam all can effectively reduce the soul syndrone intelligent weak type insomnia disorders of patients with anxiety state with PSQI,HAMA,TCM syndrome scale scores.2.Qiangpo Zhumian Decoction can improve the symptoms of insomnia and anxiety in patients with insomnia disorder accompanied by anxiety state,and its curative effect is superior to alprazolam,and can relieve the corresponding systemic symptoms,with few adverse reactions and high safety,which is worthy of further promotion.